化学物質リスク研究事業
（○：委員長）
| 青木康展 | 国立環境研究所・名誉研究員 | ||
| 専門分野 毒性学 | |||
| 青木康展、環境基準・指針値の設定の現状と今後、ファルマシア 2023；59(6):510-515. |
|||
| Aoki Y et al. Characteristic mutations induced in the small intestine of Msh2-knockout gpt delta mice. Genes Environ. 2021 Jul 5;43(1):27. doi: 10.1186/s41021-021-00196-0. | |||
| Aoki Y et al. Oxidative-stress-driven mutagenesis in the small intestine of the gpt delta mouse induced by oral administration of potassium bromate. Mutat Res. Feb-Mar 2020;850-851:503136. doi: 10.1016/j.mrgentox.2020.503136. | |||
| 池田耕一 | 公財日本建築衛生管理教育センター評議委員 | ||
| 建築衛生学 | |||
| “Study of the different Cutoff Point of the QEESI Questionnaire as a Screening Tool for Sick Building Syndrome Diagnosis in Taiwan” Koichi Ikeda, Lin-lin Huang, Sachiko Hojo, Naoki Kagi and Han-Cheng Juang, Journal of Asian Architecture and Building Engineering, vol.13 no.2, pp.1-7 2014 | |||
| 「室内環境にかかわる疾病―アレルギー、化学物質過敏症、シックハウス症候群―」池田耕一：東京電機大学出版局刊、2010 「室内空気質・温熱環境の実態と今後の課題」池田耕一：ビル用マルチパッケージ型空調システム―計画・設計から性能の評価まで―公益社団法人空気調和・衛生工学会編、2014 | |||
| 「A Study on Environmental Pollution Caused by Radioactive Substances and its Countermeasure Techniques (Part2), Radiation Dose in Park」Koichi IKEDA, Atsuo NOZAKI, Yasunori NARITA, Hoshio GOTO, Yoshihiko KANAYAMA, Kazuki IWAOKA, Hidenori YONEHARA and Hiroshi YOSHINO: Proceedings for The International Conference on Healthy Buildings 2012, pp. 1-4, 2012 | |||
| 上野 光一 | 千葉大学予防医学センター・客員教授 千葉大学・名誉教授 |
||
| 薬理学・毒性学 | |||
| （研究論文） An Alternative to Hepatotoxicity Testing Using Multicellular Spheroids Composed of Rat Liver Cells. Koichi Ueno, Ken-ichi Endoh, Aiji Miyashita, Toshiaki Takezawa, Yuichi Mori, and Tetsuo Satoh In Vitro Toxicol., 1994; 7, 351-356 |
|||
| (研究論文) Identification of an N-Terminally Acetylated Encephalitogenic Epitope in Myelin Proteolipid Apoprotein (PLP) for the Lewis Rat. Weiguo Zhao, Keith W. Wegmann, John L. Trotter, Koichi Ueno, and William F. Hickey 1994; J. Immunol., 153, 901-909 |
|||
| （著作例） Sex-related differences in pharmacokinetics and pharmacodynamics of antihypertensive drugs. Ueno K, Sato H., 2011; Hypertension Research (Review Series), 1, 1-6 |
|||
| 岡 淳一郎 | 東京理科大学薬学部 名誉教授 | ||
| 神経薬理学 | |||
| Cognitive and hippocampal synaptic profiles in monosodium glutamate-induced obese mice. S. Sasaki-Hamada, Y. Hojyo, R. Mizumoto, H. Koyama, S. Yanagisawa, J-I. Oka. Neurosci. Res. 170, 201-207 (2021). | |||
| Fluorescein permeability of the blood-brain barrier is enhanced in juvenile- but not young adult-onset type 1 diabetes in rats. Y. Tsuneoka, T. Nishimura, J-I. Oka. Biol. Pharm. Bull. 44(8), 1088-1092 (2021). |
|||
| Long-term exposure to high glucose induces changes in the expression of AMPA receptor subunits and glutamate transmission in primary cultured cortical neurons. S. Sasaki-Hamada, E. Sanai, M. Kanemaru, G. Kamanaka, J-I. Oka. Biochem. Biophys. Res. Commun. 589, 48-54 (2022). |
|||
| 代田 眞理子 | 国立大学法人東京農工大学 農学部附属感染症未来疫学研究センター 客員教授 | ||
| 生殖発生毒性学 | |||
| Dose-dependent acceleration in the delayed effects of neonatal oral exposure to low-dose 17α-ethynylestradiol on reproductive functions in female Sprague–Dawley rats. Shirota M, Kawashima J, Nakamura T, Kamiie J, Shirota K, Yoshida M. Journal of Toxicological Sciences 40: 727-738 (2015) | |||
| Delayed effects of single neonatal subcutaneous exposure of low-dose 17α-ethynylestradiol on teproductive function in female rats. Shirota M, Kawashima J, Ogawa Y, Kamiie J, Yasuno K, Shirota K, Yoshida M. Journal of Toxicological Sciences 37: 681-689 (2012) |
|||
| Internal dose-effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in gonadotropin-primed weanling rat model. Shirota M, Kaneko T, Okuyama M, Sakurada Y, Shirota K, Matsuki Y. Archives of Toxicology 81: 261-269 (2007) |
|||
| 塚本 徹哉 | 藤田医科大学医学部病理診断学 教授 | ||
| 病理学 | |||
| Ayano Michiba, Min Gi, Masanao Yokohira, Eiko Sakurai, Atsushi Teramoto, Yuka Kiriyama, Seiji Yamada, Hideki Wanibuchi, Tetsuya Tsukamoto Early Detection of Genotoxic Hepatocarcinogens in Rats Using γH2AX and Ki-67: Prediction by Machine Learning Toxicol Sci . 2023 Aug 1;kfad073. doi: 10.1093/toxsci/kfad073. Online ahead of print. PMID: 37527026 DOI: 10.1093/toxsci/kfad073 |
|||
| Sakurai, E., Ishizawa, H., Kiriyama, Y., Michiba, A., Hoshikawa, Y., Tsukamoto, T. γH2AX, a DNA Double-Strand Break Marker, Correlates with PD-L1 Expression in Smoking-Related Lung Adenocarcinoma. Int J Mol Sci 23, 2022. 10.3390/ijms23126679 |
|||
| Tetsuya Tsukamoto, Atsushi Teramoto, Ayumi Yamada, Yuka Kiriyama, Eiko Sakurai, Ayano Michiba, Kazuyoshi Imaizumi, Hiroshi Fujita Comparison of Fine-Tuned Deep Convolutional Neural Networks for the Automated Classification of Lung Cancer Cytology Images with Integration of Additional Classifiers. Asian Pac J Cancer Prev.2022 Apr 1;23(4):1315-1324. doi: 10.31557/APJCP.2022.23.4.1315. |
|||
| 信川 益明 | 医療法人社団千禮会 理事長 | ||
| 健康科学、医療科学、医療・病院管理学、環境予防医学、内科学 | |||
| 信川益明：いわゆる健康食品・機能性食品のヒト試験のあり方. 臨床薬理 2006 37(3):96-102. |
|||
| 「食品保健の科学」信川益明他共著，丸善，(2010）. |
|||
| 信川益明：新たな時代における食と健康～日本健康生活と健康科学及び第三者認証～. Health Sciences. 2021 37(1):3-21. |
|||
| 富永俊義 | 慶應義塾大学病院臨床研究推進センター特任教授 | ||
| 臨床研究 | |||
| ○ | 若林敬二 | 静岡県立大学 特任教授 | |
| 環境発がん | |||
| Wakabayashi, K., Nagao, M., Esumi, H. and Sugimura, T. Food-derived mutagens and carcinogens. Cancer Res. (Suppl.), 52: 2092s-98s (1992). | |||
| Ohe, T., Watanabe, T. and Wakabayashi, K. Mutagens in surface waters: a review. Mutat. Res., 567(2-3):109-49 (2004). | |||
| Mutoh, M., Teraoka, N., Takasu, S., Takahashi, M., Onuma, K., Yamamoto, M., Kubota, N., Iseki, T., Kadowaki, T., Sugimura, T. and Wakabayashi, K. Loss of adiponectin promotes intestinal carcinogenesis in Min and wild-type mice. Gastroenterology, 140(7):2000-8 (2011). | |||
