長寿科学政策研究事業・認知症政策研究事業

(○:委員長)
  赤池 昭紀 和歌山県立医科大学薬学部 教授
  薬理学、レギュラトリーサイエンス
  <研究論文>
Isolation of a diterpenoid substance with potent neuroprotective activity from fetal calf serum. 132.          Kume, T., Asai, N., Nishikawa, H., Mano, N., Terauchi, T., Taguchi, R., Shirakawa, H., Osakada, F., Mori, H., Asakawa, N., Yonaga, M., Nishizawa, Y., Sugimoto, H., Shimohama, S., Katsuki, H., Kaneko, S., Akaike, A., Proc. Natl. Acad. Sci. USA, 99 (5), 3288-3293,2002.
  <研究論文>
Toward the generation of rod and cone photoreceptors from mouse, monkey and human embryonic stem cells. Osakada, F., Ikeda, H., Mandai, M., Wataya, T., Watanabe, K., Yoshimura, N., Akaike, A., Sasai, Y., Takahashi, M., Nature Biotechnol., 26 (2), 215-352, 2008.
  <研究論文>
Integrin α5β1 expression on dopaminergic neurons is involved in dopaminergic neurite outgrowth on striatal neurons. Izumi, Y., Wakita, S., Kanbara, C., Nakai, T., Akaike, A., Kume, T., Sci. Rep., 7:42111. doi: 10.1038/srep42111, 2017.
       
 
 
  秋山 治彦 横浜市立脳卒中・神経脊椎センター 臨床研究部長
  神経内科特に認知症疾患
  Akiyama H, Hosokawa M, Kametani F, Kondo H, Chiba M, Fukushima M, Tabira T. Long-term oral intake of aluminium or zinc does not accelerate Alzheimer pathology in AβPP and AβPP/tau transgenic mice. Neuropathology 2012, 32:390-397.
  Akiyama H, McGeer PL,Specificity of mechanisms for plaque removal after Abeta immunotherapy for Alzheimer's disease,Nat Med 10: 117-118,2004
  Akiyama H, Kondo H, Ikeda K, Kato M, McGeer PL,Immunohistochemical localization of neprilysin in the human cerebral cortex: inverse association with vulnerability to amyloid beta-protein(Abeta) deposition,Brain Res 902:277-281,2001
       
 
 
  飯島 節 筑波大学 名誉教授
  老年医学
  Yamaguchi Y, Mori H, Ishii M, Okamoto S, Yamaguchi K, Iijima S, Ogawa S, Ouchi Y, Akishita M: Interview- and questionnaire-based surveys on elderly patients’ wishes about artificial nutrition and hydration during end-of-life care. Geratr Gerontol Int, 16: 1204-1210, 2016.
  Ouchi Y, Toba K, Ohta K, Kai I, Shimizu T, Higuchi N, Shimazono S, Iijima S, Suwa S, Nishimura M, Ninomiya H and Aita K: Guidelines from the Japan Geriatrics Society for the decision-making processes in medical and long-term care for the elderly: Focusing on the use of artificial hydration and nutrition. Geriatr Gerontol Int 18: 823–827, 2018.
  The Japanese Geriatric Society Ethics Committee: Iijima S, Aida N, Ito H, Endo H, Ohrui T, Sodei T, Toba K, Hara K, Momose Y, Uemura K, Nakano H, Miura H and Kuzuya M: Position statement from the Japan Geriatrics Society 2012: End-of-life care for the elderly. Geriatr Gerontol Int 14: 735–739, 2014.
       
 
 
  池崎 澄江 千葉大学大学院看護学研究院 教授
  老年看護学・看護管理学
  Predictors of dying at home for patients receiving nursing services in Japan. A retrospective study comparing cancer and non-cancer deaths. Ikezaki S, Ikegami N. BMC Palliat Care,10,3,2011.
  池崎澄江, 池上直己:特別養護老人ホームにおける特養内死亡の推移と関連要因の分析.厚生の指標,59(1),14-20,2012.
  藤田淳子,福井小紀子,池崎澄江,辻村真由子:在宅の介護関連職における医療職との連携困難感尺度の開発.日本公衆衛生雑誌,67(11),819-827,2020.
       
 
 
  石井 好二郎 同志社大学スポーツ健康科学部 教授
  運動療法
  地域在住高齢者における「オーラルフレイルのセルフチェック表」を用いて評価したオーラルフレイルとサルコペニア・身体的フレイルの関係. 田中大貴,大石寛,野村友哉,山口寛基,森隆彰,花野宏美,石井好二郎. 日本臨床運動療法学会誌, 23(2): 13-16, 2022.
  Phase angle from bioelectrical impedance analysis is a useful indicator of muscle quality. Akamatsu Y, Kusakabe T, Arai H, Yamamoto Y, Nakao K, Ikeue K, Ishihara Y, Tagami T, Yasoda A, Ishii K, Satoh-Asahara N. Journal of Cachexia, Sarcopenia and Muscle, 13(1): 180-189, 2021.
  Comparison of quadriceps setting strength and knee extension strength tests to evaluate lower limb muscle strength based on health-related physical fitness values in elderly people. Ito Y, Aoki T, Sato T, Oishi K, Ishii K. BMJ Open Sport Exerc Med. 2020 Jul 2;6(1):e000753.
       
 
 
鳥羽 研二 東京都健康長寿医療センター 理事長
  老年医学
  Simple screening models for cognitive impairment in community settings: The IRIDE Cohort Study. Takumi Abe, Akihiko Kitamura, Mari Yamashita, Hunkyung Kim, Shuichi P Obuchi, Tatsuro Ishizaki, Yoshinori Fujiwara, Shuichi Awata, Kenji Toba, IRIDE Cohort Study investigators. Geriatr Gerontol Int. 2022 Apr;22(4):292-297.
  Editorial: Measurable brain and cognitive reserve: The implication of neuroimaging biomarkers in the normal aging process. Chu-Chung Huang , Ching-Po Lin, Kenji Toba, Duan Xu. Front Aging Neurosci. 2022 Sep 13;14:1020435
  Organized Registration for the Assessment of Dementia by the Nationwide General Consortium Toward Effective Treatment (ORANGE) Registry: Current Status and Perspectives of Mild Cognitive Impairment. Masashi Tsujimoto , Keisuke Suzuki , Naoki Saji, Takashi Sakurai, Kengo Ito, Kenji Toba, Registry Study Group ORANGE. J Alzheimers Dis. 2022;88(4):1423-1433.
       
 
 
  中本 稔 島根県出雲保健所 所長
  公衆衛生(地域保健、職域保健)
  Response to sympathetic nervous system to cold exposure in vibration syndrome subjects and age-matched healthy controls.
Minoru Nakamoto. Int Arch Occup Environ Health.62:177-181,1990.
  Pituitary-thyroid function in vibration syndrome patients.
Minoru Nakamoto, Noriakki Hadara, Yoshitaka Kinukawa.
Ind Health. 28:199-202,1990.
  家庭奉仕員と特別養護老人ホーム寮母の疲労に関する研究.
中本稔、原田規章、涌井忠明.
産業衛生学雑誌. 37suppl;365,1995.
       
 
 
  和田 健二 川崎医科大学認知症学 教授
  認知症
  ABC Dementia Scale Classifies Alzheimer's Disease Patients into Subgroups Characterized by Activities of Daily Living, Behavioral and Psychological Symptoms of Dementia, and Cognitive Function.
Wada-Isoe K, Kikuchi T, Umeda-Kameyama Y, Mori T, Akishita M, Nakamura Y; ABC Dementia Scale Research Group.
J Alzheimers Dis. 2020;73(1):383-392.
  Validation of the Neuropsychiatric Inventory Based on Item Response Theory.
Wada-Isoe K, Kikuchi T, Umeda-Kameyama Y, Mori T, Akishita M, Nakamura Y.J Alzheimers Dis Rep. 2020 May 20;4(1):151-159.
  Global Clinical Dementia Rating Score of 0.5 May Not Be an Accurate Criterion to Identify Individuals with Mild Cognitive Impairment.
Wada-Isoe K, Kikuchi T, Umeda-Kameyama Y, Mori T, Akishita M, Nakamura Y; ABC Dementia Scale Research Group.
J Alzheimers Dis Rep. 2019 Sep 10;3(1):233-239.