循環器疾患・糖尿病等生活習慣病対策総合研究事業
（○：委員長）
| ○ | 水澤 英洋 | 国立研究開発法人国立精神・神経医療研究センター・理事長特任補佐 | |
| 神経内科学 | |||
| Mitsui J, Matsukawa T, Uemura Y, Kawahara T, Chikada A, Porto KJL, Naruse H,Tanaka M, Ishiura H, Toda T, Kuzuyama H, Hirano M, Wada I, Ga T, Moritoyo T,Takahashi Y, Mizusawa H, Ishikawa K, Yokota T, Kuwabara S, Sawamoto N, TakahashiR, Abe K, Ishihara T, Onodera O, Matsuse D, Yamasaki R, Kira JI, Katsuno M,Hanajima R, Ogata K, Takashima H, Matsushima M, Yabe I, Sasaki H, Tsuji S. High-dose ubiquinol supplementation in multiple-system atrophy: a multicentre,randomised, double-blinded, placebo-controlled phase 2 trial. EClinicalMedicine.2023 Apr 14; 59:101920. doi: 10.1016/j.eclinm. | |||
| Hamanaka K, Yamauchi D, Koshimizu E, Watase K, Mogushi K, Ishikawa K, Mizusawa H, Tsuchida N, Uchiyama Y, Fujita A, Misawa K, Mizuguchi T, Miyatake S, Matsumoto N. Genome-wide identification of tandem repeats associated with splicing variation across 49 tissues in humans. Genome Res. 2023 Mar;33(3):435-447. doi: 10.1101/gr.277335.122. | |||
| Honda T, Matsumura K, Hashimoto Y, Yokota T, Mizusawa H, Nagao S, Ishikawa K. Temporal Relationship between Impairment of Cerebellar Motor Learning and Deterioration of Ataxia in Patients with Cerebellar Degeneration. Cerebellum. 2023 Apr 28. doi: 10.1007/s12311-023-01545-1. Epub ahead of print. | |||
| 川上 康 | 筑波大学医学医療系 教授 筑波大学附属病院 副病院長 |
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| 代謝内分泌内科学 | |||
| The redox status of cysteine thiol residues of apolipoprotein E impacts on its lipid interactions. Yamauchi K, Kawakami Y. Biol Chem. 2020 Apr 28;401(5):617-627. |
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| The impact of right bundle branch block on right ventricular size and function assessed by three-dimensional speckle-tracking echocardiography. Nakazawa N, Ishizu T, Seo Y, Kawamatsu N, Sato K, Yamamoto M, Machino-Ohtsuka T, Horigome H, Hiramatsu Y, Ieda M, Kawakami Y.Heart Vessels. 2020 Apr;35(4):576-585. |
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| Left Ventricular Longitudinal Strain as a Marker for Point of No Return in Hypertensive Heart Failure Treatment. Ishizu T, Seo Y, Namekawa M, Murakoshi N, Ieda M, Kawakami Y.J Am Soc Echocardiogr. 2020 Feb;33(2):226-233. |
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| 合田 敏尚 | 静岡県立大学食品栄養科学部 特任教授 | ||
| 栄養生理学 | |||
| Self-reported faster eating is positively associated with accumulation of visceral fat in middle-aged apparently healthy Japanese men. Mochizuki K, Yamada M, Miyauchi R, Misaki Y, Kasezawa N, Tohyama K, Goda T. Eur J Nutr. 53: 1187-1194, 2014. | |||
| The alpha-glucosidase inhibitor miglitol decreases glucose fluctuations and inflammatory cytokine gene expression in peripheral leukocytes of Japanese patients with type 2 diabetes. Osonoi T, Saito M, Mochizuki K, Fukaya N, Muramatsu T, Inoue S, Fuchigami M, Goda T. Metabolism 59: 1816-1822, 2010. | |||
| Availability, fermentability and energy value of resistant maltodextrin: A modeling of short-term indirect calorimetry measurements in healthy adults. Goda T, Kajiya Y, Suruga K, Tagami H, Livesey G. Am J Clin Nutr. 83: 1321-1330, 2006. | |||
| 齊藤 延人 | 国立大学法人東京大学 理事、副学長、教授 | ||
| 脳神経外科学 | |||
| Dofuku S, Sonehara K, Miyawaki S, Sakaue S, Imai H, Shimizu M, Hongo H, Shinya Y, Ohara K, Teranishi Y, Okano A, Ono H, Nakatomi H, Teraoka A, Yamamoto K, Maeda Y, Nii T, Kishikawa T, Suzuki K, Hirata J, Takahashi M, Matsuda K, Kumanogoh A, Matsuda F, Okada Y, and Saito N. Genome-Wide Association Study of Intracranial Artery Stenosis Followed by Phenome-Wide Association Study. Transl Stroke Res 2023 Jun;14(3):322-333. doi: 10.1007/s12975-022-01049-w. | |||
| Hongo H, Miyawaki S, Teranishi Y, Ishigami D, Ohara K, Sakai Y, Shimada D, Umekawa M, Koizumi S, Ono H, Nakatomi H, and Saito N. Genetics of brain arteriovenous malformations and cerebral cavernous malformations. J Hum Genet. 2023 Mar;68(3):157-167. doi: 10.1038/s10038-022-01063-8. | |||
| Shinya Y, Hasegawa H, Kawashima M, Koizumi S, Katano A, Umekawa M, and Saito N. Prognosis of Rotational Angiography-Based Stereotactic Radiosurgery for Dural Arteriovenous Fistulas: A Retrospective Analysis. Neurosurgery. 2023 Jan 1;92(1):167-178. doi: 10.1227/neu.0000000000002168. | |||
| 下光 輝一 | 公益財団法人健康・体力づくり事業財団 理事長 東京医科大学 名誉教授 |
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| 公衆衛生学、循環器予防医学、体力科学 | |||
| Kikuchi, H., Odagiri, Y., Ohya, Y., Nakanishi, Y.*, Shimomitsu, T., Theorell, T.*, Inoue, S. Association of overtime work hours with various stress responses in 59,021 Japanese workers: Retrospective cross-sectional study. PLoS ONE 15 (3): e0229506, 2020 | |||
| Tsuno, K.*, Kawakami, N.*, Tsutsumi, A.*, Shimazu, A.*, Inoue, A.*, Odagiri, Y., Yoshikawa, T.*, Haratani, T.*, Shimomitsu, T., Kawachi, I.*. Socioeconomic determinants of bullying in the workplace: a national representative sample in Japan. PLOS ONE 10(3): e0119435, 2015 | |||
| Dwyer, T., Iwane, H., Dean, K., Odagiri, Y., Shimomitsu, T., Blizzard, L., Srinivasan, S., Nicklas, T., Wattigney, W., Riley, M., Berenson, G., Differences in HDL cholesterol concentrations in Japanese, American, and Australian children, Circulation 96(9): 2830-2836, 1997 | |||
| 代田 浩之 | 順天堂大学保健医療学部 学部長 順天堂大学大学院医学研究科循環器内科学 特任教授 |
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| 循環器内科学 | |||
| Relationship Between Kihon Checklist Score and Anxiety Levels in Elderly Patients Undergoing Early Phase II Cardiac Rehabilitation. Honzawa A, Nishitani-Yokoyama M, Shimada K, Kunimoto M, Yamada M, Matsubara T, Matsumori R, Fujiwara K, Abulimiti A, Aikawa T, Ouchi S, Shimizu M, Sugita Y, Shimada A, Yamamoto T, Amano A, Asai T, Saito M, Morisawa T, Takahashi T, Fujiwara T, Daida H, Minamino T. CARDIOLOGY RESEARCH 2020, 11(6): 405-411 | |||
| Effect of pemafibrate (K-877) a novel selective peroxisome proliferator-activated receptor alpha modular (SPPARM alpha) in atherosclerosis model using low density lipoprotein receptor knock-out swine with balloon injury. Konishi H, Miyauchi K, Onishi A, Suzuki S, Fuchimoto D, Shitara J, Endo H, Wada H, Doi S, Naito R, Ogita M, Dohi T, Kasai T, Daida H. PLOS ONE 2020, 15(11): e0241195 | |||
| Preliminary Pilot Study of Combined Effects of Physical Activity and Achievement of LDL-Cholesterol Target on Coronary Plaque Volume Changes in Patients with Acute Coronary Syndrome. Nishitani-Yokoyama M, Miyauchi K, Shimada K, Yokoyama T, Ouchi S, Aikawa T, Kunimoto M, Yamada M, Honzawa A, Okazaki S, Tsujita H, Koba S, Daida H. JOURNAL OF CLINICAL MEDICINE 2020, 9(5): 1578 | |||
| 中村 好一 | 自治医科大学 教授 | ||
| 疫学・公衆衛生学 | |||
| 中村好一．疫学と統計手法：特に因果関係を中心に（科学と裁判）．判例時報 2020：2446号：106-110． | |||
| Ae R, Makino N, Kosami K, Kuwabara M, Matsubara Y, Nakamura Y. Epidemiology, treatments, and cardiac complications in patients with Kawasaki disease: The nationwide survey in Japan, 2017-2018. J Pediatr 2020; 225: p23-29.e2. doi:10.1016/j.jpeds.2020.05.034. |
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| 中村好一．基礎から学ぶ楽しい疫学 第４版．東京：医学書院，2020． | |||
| 成松 英智 | 札幌医科大学医学部救急医学講座 教授 附属病院高度救命救急センター センター長 北海道病院前・航空・災害医学寄付講座 兼任教授 |
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| 救急医学、集中治療医学、麻酔科学 | |||
| Narimatsu E, Kakizaki R, Nomura K, Sawamoto K, Takahashi K, Uemura S, Ishiguro M. Dexmedetomidine improves excessive extracellular glutamate-induced synaptic depression.Brain Res. 2022 Aug:1789:147949. | |||
| Narimatsu E, Niiya T, Takada Y, Takahashi K, Yamauchi M, Yamakage M. Blockers of adenosine A1, but not muscarinic acetylcholine, receptors improve excessive extracellular glutamate-induced synaptic depression. Neurosci Res. 2013 Feb;75(2):103-11. | |||
| Narimatsu E, Niiya T, Takahashi K, Yamauchi M, Yamakage M. Pralidoxime inhibits paraoxon-induced depression of rocuronium-neuromuscular block in a time-dependent fashion. Am J Emerg Med. 2012 Jul;30(6):901-7. | |||
| 三嶋 理晃 | 大阪府済生会野江病院 院長、総長 京都大学 名誉教授 |
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| 呼吸器内科 | |||
| Setoh K, Terao C, Muro S, Kawaguchi T, Tabara Y, Takahashi M, Nakayama T, Kosugi S, Sekine A, Yamada R, Mishima M, Matsuda F. Three missense variants of metabolic syndrome-related genes are associated with alpha-1 antitrypsin levels. Nat Commun. 2015; 6: 7754. | |||
| Setoh K, Terao C, Muro S, Kawaguchi T, Tabara Y, Takahashi M, Nakayama T, Kosugi S, Sekine A, Yamada R, Mishima M, Matsuda F. Three missense variants of metabolic syndrome-related genes are associated with alpha-1 antitrypsin levels. Nat Commun. 2015; 6: 7754. | |||
| Yamamoto Y, Gotoh S, Korogi Y, Seki M, Konishi S, Ikeo S, Sone N, Nagasaki T, Matsumoto H, Muro S, Ito I, Hirai T, Kohno T, Suzuki Y, Mishima M.Long-term expansion of alveolar stem cells derived from human iPS cells in organoids. Nat Methods. 2017; 14(11): 1097-1106. | |||
| 森本 明子 | 大阪公立大学大学院 看護学研究科 看護情報学 教授 | ||
| 看護情報学、成人保健学 | |||
| Relationship between communicative and critical health literacy, health information sources, and participation in health checkups among middle-aged Japanese community residents. Morimoto A, Koh C, Yasumoto R, Furuki H, Watanabe K, Tsuzuki C, Sonoda N. Preventive Medicine. 2022; 161: 107112. |
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| Impact of impaired insulin secretion and insulin resistance on the incidence of type 2 diabetes mellitus in a Japanese population: the Saku study. Morimoto A, Tatsumi Y, Deura K, Mizuno S, Ohno Y, Miyamatsu N, Watanabe S. Diabetologia. 2013; 56(8): 1671-1679. |
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| 標準保健師講座 疫学・保健統計学 第3版. 牧本清子, 尾﨑米厚, 森本明子, 宮松直美. 医学書院. 2015. |
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| 安井 利一 | 明海大学 学長、教授 | ||
| 口腔衛生学、健康科学、公衆衛生学 | |||
| 新編衛生学・公衆衛生学・安井利一 他・医歯薬出版株式会社・2021年 | |||
| Quantification of the Ability of Natural Products to Prevent Herpes Virus Infection. Fukuchi K, Sakagami H, Sugita Y, Takao K, Asai D, Terakubo S, Takemura H, Ohno H, Horiuchi M, Suguro M, Fujisawa T, Toeda K, Oizumi H, Yasui T, Oizumi T. Medicines (Basel). 2020 Oct 6;7(10) | |||
| クマ笹葉アルカリ抽出液（ササヘルス®）は，瞬間的にウイルスを不活化する。坂上宏、福地邦彦、 浅井大輔、寺久保繁美、竹村弘、堀内美咲、藤澤知弘、勝呂まどか、戸枝一喜、安井利一、大泉浩史、大泉高明、New Food Industry 62(11): 785-790. 2020. | |||
| 横山 啓太郎 | 慈恵医大晴海トリトンクリニック所長 東京慈恵会医科大学 大学院 健康科学教授 |
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| 慢性腎臓病、高血圧 | |||
| Randomised clinical trial of ferric citrate hydrate on anaemia management in haemodialysis patients with hyperphosphataemia: ASTRIO study. Yokoyama K, Fukagawa M, Akiba T, Nakayama M, Ito K, Hanaki K, Wolf M, Hirakata H. Sci Rep. 2019 Jun 20;9(1):8877. Long-Term Efficacy and Safety of Evocalcet in Japanese Patients with Secondary Hyperparathyroidism Receiving Hemodialysis. Yokoyama K, Shimazaki R, Fukagawa M, Akizawa T; Evocalcet Study Group. Sci Rep. 2019 Apr 23;9(1):6410. Safety and efficacy of etelcalcetide, an intravenous calcimimetic, for up to 52 weeks in hemodialysis patients with secondary hyperparathyroidism: results of a post-marketing surveillance in Japan. Yokoyama K, Fukagawa M, Shigematsu T, Akiba T, Yoshikawa K, Tsuchiya A, Kuwabara M, Akizawa T. Clin Exp Nephrol. 2021 Jan;25(1):66-79. Ferric citrate hydrate is associated with a reduced cost of drugs and a smaller change in red blood cell distribution width. Ito K, Yokoyama K, Nakayama M, Fukagawa M, Hirakata H.Sci Rep. 2022 Feb 14;12(1):2406 |
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| 「健康をマネージメントする」横山啓太郎 単著, C.C.C.メディアハウス, (2019). 「生活習慣病克服プログラム」横山啓太郎 単著, 学研プラス(2021) |
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| Effect of Ferric Citrate Hydrate on Fibroblast Growth Factor 23 and Serum Alpha-Klotho in Hemodialysis Patients with Hyperphosphatemia, under Serum Phosphate Level was maintained: ASTRIO Study, Supplementary Analysis. Yokoyama K. Fukagawa M, AkibaT, Nakayama M, Hanaki K, Kyoko I, Hirakata H N. American Society of Nephrology Kidney Week New Orleans. 2018 Nov. （J Am Soc Nephrol.掲載） Ferric citrate hydrate improves levels of transferrin saturation in hemodialysis patients with lower levels of transferrin saturation the 59th ERA Congress Paris & Virtual (May 19-22, 2022). Mini-Oral online |
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| 吉池 信男 | 青森県立保健大学 理事長、学長 健康科学部栄養学科 教授 |
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| 栄養学、公衆衛生学 | |||
| Validation of the most cost-effective nudge to promote workers' regular self-weighing: a cluster randomized controlled trial. Takebayashi M, Yoshiike N, Koyama T, Toriyabe M, Nakamura H, Takebayashi K.Sci Rep. 2022 Sep 15;12(1):15501. |
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| Mindful Eating Proficiency and Healthy Eating Literacy among Japanese Mothers: Associations with Their Own and Their Children's Eating Behavior. Nakamura T, Akamatsu R, Yoshiike N. Nutrients. 2021 Dec 11;13(12):4439. |
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| Association between Parent and Child Dietary Sodium and Potassium Intakes: Aomori Prefectural Health and Nutrition Survey, 2016. Koyama T, Yoshiike N.Nutrients. 2019 Jun 23;11(6):1414. |
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