新興・再興感染症及び予防接種政策推進研究事業
（○：委員長）
| ○ | 脇田隆字 | 国立感染所・所長 | |
| ウイルス学、肝炎ウイルス学 | |||
| Wakita T, T Pietschmann, T Kato, T Date, M Miyamoto, Z Zhao, K Murthy, A Habermann, H-G Krausslich, M Mizokami, R Bartenschlager, T J Liang. Production of Infectious Hepatitis C Virus in Tissue Culture from a Cloned Viral Genome. Nat Med. 2005 11:791-6. | |||
| Wakita T and Wands JR. Specific inhibition of hepatitis C virus expression by antisense oligodeoxy-nucleotides: In vitro model for selection of target sequence. J Biol Chem. 1994 269:14205-10 | |||
| Wakita T, Kakumu S, Shibayama M, Yoshioka K, Ito Y, Shinagawa T, Ishikawa T, Takayanagi M, Morishima T. Detection of pre-C and core region mutants of hepatitis B virus in chronic hepatitis B virus carriers. J Clin Invest. 1991 88: 1793-801 | |||
| 喜田 宏 | 北海道大学 人獣共通感染症国際共同研究所 特別招聘教授 統括 | ||
| ウイルス学、人獣共通感染症学、ワクチン学 | |||
| 「人獣共通感染症 初・改訂２と３版」喜田 宏 他共著,木村 哲/喜田 宏 編, 医薬ジャーナル社 (2004,2011と2016) | |||
| Nomura N, Matsuno K, Shingai M, Ohno M, Sekiya T, Omori R, Sakoda Y, Webster RG, Kida H: Updating the influenza virus library at Hokkaido University -It's potential for the use of pandemic vaccine strain candidates and diagnosis. Virology 557:55-61, 2021. | |||
| Shingai M, Nomura N, Sekiya T, Ohno M, Fujikura D, Handabile C, Omori R, Ohara Y, Nishimura T, Endo M, Kimachi K, Mitsumata R, Ikeda T, Kitayama H, Hatanaka H, Sobue T, Muro F, Suzuki S, Thanh Nguyen C, Ishigaki H, Nakayama M, Mori Y, Itoh Y, Koutsakos M, Chua B.Y, Kedzierska K, Brown L.E, Jackson D.C, Ogasawara K, Kino Y, Kida H: Potent priming by inactivated whole influenza virus particle vaccines is linked to viral RNA uptake into antigen presenting cells. Vaccine 39:3940-3951, 2021. | |||
| 遠藤弘良 | 聖路加国際大学名誉教授 | ||
| 公衆衛生学、国際保健 | |||
| （研究論文） S.Miyano,G.Syakantu, K.Komada, H.Endo, T.Sugishita, Cost-effectiveness analysis of the national decentralization policy of antiretroviral treatment programme in Zambia, Cost Effectiveness and Resource Allocation, 2017, 15:4, |
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| （報告書） F.Harvey,H.Endo et al., A report by the Independent Oversight and Advisory Committee for the WHO Health Emergency Programme, 2019 |
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| （報告書） F.Harvey,H.Endo et al., A report by the Independent Oversight and Advisory Committee for the WHO Health Emergency Programme, 2020 |
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| 山崎晋一朗 | 千葉県病院局病院局長 | ||
| 専門分野：医療行政 | |||
| 特になし |
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| （業績・実績その２） | |||
| （業績・実績その３） | |||
| 小池和彦 | 関東中央病院・病院長 | ||
| 専門分野 内科学、感染症、消化器 | |||
| Hirano J, Yoshio S, Sakai Y, Songling L, Suzuki T, Itoh Y, Zhang H, Chen DV, Haga S, Oomori H, Kodama T, Maeda Y, Ono Y, Takahashi Y, Standley DM, Yamamoto M, Moriishi K, Moriya K, Kanto T, Takehara T, Koike K, Matsuura Y, Okamoto T. Hepatitis C virus modulates signal peptide peptidase to alter host protein processing. Proc Natl Acad Sci U S A 2021 Jun 1;118(22):e2026184118. | |||
| Shinohara T, Otani A, Yamashita M, Wakimoto Y, Jubishi D, Okamoto K, Kanno Y, Ikeda M, Ishigaki K, Nakai Y, Harada S, Okugawa S, Koike K, Moriya K. Acute Pancreatitis During COVID-19 Pneumonia. Pancreas 2020 Nov/Dec;49(10):e106-e108. | |||
| Hatakeyama S, Sugaya N, Ito M, Yamazaki M, Ichikawa M, Kimura K, Kiso M, Shimizu H, Kawakami C, Koike K, Mitamura K, Kawaoka Y. Emergence of Influenza B Viruses With Reduced Sensitivity to Neuraminidase Inhibitors. JAMA 2007;297:1435-1442. | |||
| 笹川千尋 | 千葉大学真菌医学研究センター・センター長 一般財団法人日本生物科学研究所・所長 （東京大学名誉教授） |
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| 微生物学、感染症学、免疫学 | |||
| Isolation and characterization of Helicobacter suis from huma stomach. Rimbara E, Suzuki M, Matsui H, Nakamura M, Morimoto M, Sasakawa C, Matsuda H, Nomura S, Osaki T, Nagata N, Shibayama K, Tokunaga K. Proc Natl Acad Sci USA. 2021 Mar; 118(13):e2026337118.doi. | |||
| Shigella infection and host cell death: a double-edged sword for the host and pathogen survival. Ashida H, Suzuki T, Sasakawa C. Curr Opin Microbiol. 2021. Feb; 59:1-7. | |||
| Bacterial artificial chromosome-based reverse genetics system for cloning and manipulation of the full-length genome of infectious bronchitis virus. Inayoshi Y, Ogura S, Tanahashi E, Lin E, Kawaguchi Y, Kodama T, Sasakawa C. Curr Res Microb Sci. 2022. 13;3:100155. | |||
| 堀田 博 | 神戸大学・名誉教授 甲南女子大学・研究倫理アドバイザー |
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| 専門分野：ウイルス学、微生物感染症学 | |||
| M protein of subacute sclerosing panencephalitis virus, synergistically with the F protein, plays a crucial role in viral neuropathogenicity. Satoh Y, Higuchi K, Nishikawa D, Wakimoto H, Konami M, Sakamoto K, Kitagawa Y, Gotoh B, Jiang DP, Hotta H, Itoh M. Journal of General Virology. 102(10): 001682, 2021. |
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| Identification of an antiviral component from the venom of the scorpion Liocheles australasiae using venom gland transcriptome analysis. Miyashita M, Mitani N, Kitanaka A, Yakio M, Chen M, Nishimoto S, Uchiyama H, Sue M, Hotta H, Nakagawa Y, Miyagawa. Toxicon. 191(2), 25-37, 2021. |
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| 医学教科書「コンパクト微生物学 改訂第5版」小熊惠二，堀田博 (監修), 林俊治, 石戸聡 (編集), 南江堂，2021. | |||
| 森 亨 | （公財）結核予防会結核研究所名誉所長 | ||
| 結核・公衆衛生 | |||
| Mori T: BCG vaccination in control of tuberculosis. (in: Takii T, Maeyama J, Yamamoto S (ed): BCG 2nd Edition -TB vaccine- Application against tuberculosis and other diseases. Japan Anti-Tuberculosis Association, Tokyo, 2022) pp 11-46. |
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| 森 亨・岡輝明：剖検記録からみた最近の結核臨床診断の精度．結核 96(1): 1-5, 2021 |
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| 國分恵子・堀口美奈子・森 亨：介護保険初申請後５年間の認知症・障害者自立度の変化とその関連要因を探る．厚生の指標 69(11): 17-22, 2022 |
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| 髙子 徹 | AMED 科学技術顧問 | ||
| 薬理、創薬科学 | |||
| Affinity and kinetic analysis of the molecular interaction of ICAM-1 and leukocyte function-associated antigen-1.: Tominaga Y, Kita Y, Satoh A, Asai S, Kato K, Ishikawa K, Horiuchi T, Takashi T. , J. Immunol. 1998, 161(8), 4016-4022 | |||
| Development of a cell-free binding assay for a rat ICAM-1/LFA-1 interactions using a novel anti-rat LFA-1 monoclonal antibody and comparison with a cell-based assay.: Mukasa R, Satoh A, Tominaga Y, Yamazaki M, Matsumoto K, Iigo Y, Higashida T, Kita Y, Miyasaka M, Takashi T. , J. Immumol. Methods. 1999, 228(1-2), 69-79 |
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| Discovery of trans-[1-[[2,5-Dichloro-4-(1-methyl-3-indolylcarboxamido)phenyl] acetyl]-(4S)-methoxy-(2S)-pyrrolidinylmethoxy]cyclohexanecarboxylic acid: an orally active, selective very late antigen-4 antagonist.: Muro F, Iimura S, Sugimoto Y, Yoneda Y, Chiba J, Watanabe T, Setoguchi M, Iigo Y, Matsumoto K, Satoh A, Takayama G, Taira T, Yokoyama M, Takashi T, Nakayama A, Machinaga N., J. Med. Chem. 2009, 52(24), 7974-7992 |
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