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脇田 隆字 |
国立感染症研究所・所長 |
| ウイルス学、肝炎ウイルス学 |
| Wakita T, T Pietschmann, T Kato, T Date, M Miyamoto, Z Zhao, K Murthy, A Habermann, H-G Kra:usslich, M Mizokami, R Bartenschlager, T J Liang. Production of Infectious Hepatitis C Virus in Tissue Culture from a Cloned Viral Genome. Nat Med. 2005 11:791-6.
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| Wakita T and Wands JR. Specific inhibition of hepatitis C virus expression by antisense oligodeoxy-nucleotides: In vitro model for selection of target sequence. J Biol Chem. 1994 269:14205-10
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| Wakita T, Kakumu S, Shibayama M, Yoshioka K, Ito Y, Shinagawa T, Ishikawa T, Takayanagi M, Morishima T. Detection of pre-C and core region mutants of hepatitis B virus in chronic hepatitis B virus carriers. J Clin Invest. 1991 88: 1793-801
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相澤 好治 |
北里大学・名誉教授 |
| 予防医学 |
| Aizawa Y, Kudo Y. Magnetometric evaluation of toxicities of chemicals to the lungs and cells.Environ Health Prev Med. 2010 Jul;15(4):197-202. (Epub 2010 Apr 6.)
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| Wada K, Yoshikawa T, Hayashi T, Aizawa Y. Emergency response technical work at Fukushima Dai-ichi nuclear power plant: occupational health challenges posed by the nuclear disaster. Occup Environ Med 2012.8, 69(8):599-602. Epub 2012 Apr 12.
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| Kido T, Sugaya C, Ikeuchi R, Kudo Y, Tsunoda M, Aizawa Y. The increases in mRNA expressions of inflammatory cytokines by adding cleaning solvent or tetrachloroethylene in the murine macrophage cell line J774.1 evaluated by real-time PCR. Ind Health. 2013;51(3):319-25. Epub 2013 Mar 29.
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井上 真奈美 |
国立研究開発法人 国立がん研究センター 社会と健康研究センター 予防研究部・部長 |
| 疫学、予防医学 |
| Inoue M, et al. Coffee Drinking and Reduced Risk of Liver Cancer: Update on Epidemiological Findings and Potential Mechanisms. Curr Nutr Rep 2019; 8: 182-186.
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| Inoue M, et al. Attributable causes of cancer in Japan in 2005--systematic assessment to estimate current burden of cancer attributable to known preventable risk factors in Japan. Ann Oncol 2012; 23: 1362-1369.
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| Inoue M, et al. Metabolic factors and subsequent risk of hepatocellular carcinoma by hepatitis virus infection status: a large-scale population-based cohort study of Japanese men and women (JPHC Study Cohort II). Cancer Causes Control 2009; 20: 741-750.
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井廻 道夫 |
新百合ヶ丘総合病院消化器・肝臓病研究所・所長 |
| 肝臓病学 |
| Perforin, Fas/Fas ligand, TNF-a pathways as specific and bystander killing mechanisms of hepatitis C virus-specific human CTL. Ando K, Hiroishi K, Kaneko T, Moriyama T, Muto Y, Kayagaki N, Yagita H, Okumura K, Imawari M. J Immunol 1997;158:5283-5291.
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| Strong CD8+ T-cell responses against tumor-associated antigens prolong the recurrence-free interval after tumor treatment in patients with hepatocellular carcinoma. Hiroishi K, Eguchi J, Baba T, Shimazaki T, Ishii S, Hiraide A, Sasaki M, Doi H, Uozumi S, Omori R, Matsumura T, Yanagawa T, Ito T, Imawari M. J Gastroenterol 2010;45:451-458.
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| 25-hydroxyvitamin D3 suppresses hepatitis C virus production. Matsumura T, Kato T, Sugiyama N, Tasaka-Fujita M, Murayama A, Masaki T, Wakita T, Imawari M. Hepatology 2012;56:1231-1239.
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遠藤 弘良 |
聖路加国際大学名誉教授 |
| 国際保健、公衆衛生 |
| S.Miyano,G.Syakantu, K.Komada, H.Endo, T.Sugishita, Cost-effectiveness analysis of the national decentralization policy of antiretroviral treatment programme in Zambia, Cost Effectiveness and Resource Allocation, 2017, 15:4,
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| W.Paoin, M.Yuenyongsuwan, Y.Yokobori, H.Endo, S.Kim, Development of the ICD-10 simplified version and field test, Professional practice and innovation, 2017
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| F.Harvey,H.Endo et al., A report by the Independent Oversight and Advisory Committee for the WHO Health Emergency Programme, 2019
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恩地 森一 |
愛媛大学 名誉教授 |
| 消化器・代謝内科学 |
Akbar SMF, Yoshida O, Onji M, et al:
Immune modulator and antiviral potential of dendritic cells pulsed with both hepatitis B surface antigen and core antigen for treating chronic HBV infection. Antivir Ther:887-895, 2010
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| Kawasaki K, Abe M, Onji M, et al: Blockade of B-cell-activating factor signaling enhances hepatic steatosis induced by a high-fat diet and improves insulin sensitivity. Lab Invest, 93(3):311-21, 2013
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| Al Mahtab M, Akbar SMF, Onji M, et al: Treatment of chronic hepatitis B na?ve patients with a therapeutic vaccine containing HBs and HBc antigens(A randomaized, open and treatment controlled phase Ⅲ clinical trial). PLoS One, 13:e020123, 2018
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吉澤 要 |
国立病院機構信州上田医療センター・名誉院長 |
| 肝臓病学 |
| Long-term outcome of Japanese patients with type 1 autoimmune hepatitis. Yoshizawa K, Matsumoto A, Ichijo T, Umemura T, Joshita S, Komatsu M, Tanaka N, Tanaka E, Ota M, Katsuyama Y, Kiyosawa K, Abe M, Onji M. Hepatology. 2012 Feb; 56:668-676.
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| Clinical features of autoimmune hepatitis with acute presentation: a Japanese nationwide survey. Joshita S, Yoshizawa K, Umemura T, Ohira H, Takahashi A, Harada K, Hiep NC, Tsuneyama K, Kage M, Nakano M, Kang JH, Koike K, Zeniya M, Yasunaka T, Takaki A, Torimura T, Abe M, Yokosuka O, Tanaka A, Takikawa H; Japan Autoimmune Hepatitis Study Group (JAIHSG). J Gastroenterol. 2018 Feb;53：1079-1088
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| 「肝胆膵 肝疾患の地域連携医療―肝疾患診療連携拠点病院、公費助成制度、治療計画の運用 長野県の取り組み」吉澤 要 アークメディア （2010）.
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林 紀夫 |
関西労災病院・院長 |
| 肝臓病学 |
| Quantitative analysis of pre-S1 and pre-S2 in relation to HBsAg expression. Yuki N, Hayashi N, Katayama K, Kasahara A, Ueda K, Fusamoto H, Sato N, Kamada T. Hepatology 11:38-43, 1990 |
Identification of multiple transcription factors, HLF, FTF, and E4BP4, controlling hepatitis B virus enhancer II. Ishida H, Ueda K, Ohkawa K, Kanazawa Y, Hosui A, Nakanishi F, Mita E, Kasahara A, Sasaki Y, Hori M, Hayashi N.
J Virol 74:1241-1251,2000
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Supportive role played by precore and preS2 genomic changes in the establishment of lamivudine-resistant hepatitis B virus. Ohkawa K, Takehara T, Kato M, Deguchi M, Kagita M, Hikita H, Sasakawa A, Kohga K, Uemura A, Sakamori R, Yamaguchi S, Miyagi T, Ishida H, Tatsumi T, Hayashi N.
J Infect Dis 198:1150-1159, 2008
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宮村 達男 |
国立感染症研究所・名誉所員 |
| ウイルス学 |
| An assay for circulating antibodies to a major etiologic virus of human non-A, non-B hepatitis. Kuo,G., Choo,Q-L., Alter,H.J., Gitnick,G.L., Redeker,A.G., Purcell,R.H., Miyamura,T. Dienstag J.L., Alter,M.J., Stevens,C.E., Tegtmeier,G.E., Bonino,F., Colombo,M., Lee,W-S., Kuo,C., Berger,K., Shuster,J.R., Overby,L.R., Bradley,D.W., and Houghton,M. Science 244: 362-364, 1989. |
| Detection of antibody against antigen expressed by molecularly cloned hepatitis C virus cDNA: Application to diagnosis and blood screening for post transfusion hepatitis. Miyamura,T., Saito,I., Katayama,T., Kikuchi,S., Tateda,A., Houghton,M., Choo,Q-L., and Kuo,G. Proc.Natl.Acad.Sci.USA, 87: 983-987, 1990. |
| A cDNA fragment of hepatitis C virus isolated from an implicated donor of post-transfusion non-A, non-B hepatitis in Japan. Kubo,Y., Takeuchi,K., Boonmar,S., Katayama,T., Choo,Q-L., Kuo,G., Weiner,A.W., Bradley,D.W., Houghton,M., Saito,I., and Miyamura,T. Nucl.Acids Res. 17:10367-10372, 1989. |
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