ホーム > 政策について > 分野別の政策一覧 > 他分野の取り組み > 研究事業 > 令和2年度 厚生労働科学研究の概要 > 事前評価委員会名簿 > 難治性疾患政策研究事業事前評価委員名簿

難治性疾患政策研究事業事前評価委員名簿

(○:委員長)

 
新井 一 順天堂大学 学長
脳神経外科
Mori E, Ishikawa M, Kato T, Kazui H, Miyake H, Miyajima M, Nakajima M, Hashimoto M, Kuriyama N, Tokuda T, Ishii K, Kaijima N, Hirata Y, Saito M, Arai H: Guidelines for management of idiopathic normal pressure hydrocephalus: Second edition. Neurol Med Chir (Tokyo) 52:775-809, 2012
Sugano H, Nakanishi H, Nakajima M, Higo T, Iimura Y, Tanaka K, Hosozawa M, Niijima S, Arai H. Posterior quadrant disconnection surgery for Sturge-Weber syndrome. Epilepsia 55(5):683-9, 2014
Iihara K, Tominaga T, Saito N, Suzuki M, Date I, Fujii Y, Hongo K, Houkin K, Kato A, Kato Y, Kawamata T, Kim P, Kinouchi H, Kohmura E, Kurisu K, Maruyama K, Mikuni N, Miyamoto S, Morita A, Nakase H, Narita Y, Nishikawa R, Nozaki K, Ogasawara K, Ohata K, Sakai N, Sakamoto H, Shiokawa Y, Sonoda Y, Takahashi JC, Ueki K, Wakabayashi T, Yamamoto T, Yoshida K, Kayama T, Arai H; Japan Neurosurgical Society. The Japan Neurosurgical Database: Overview and Results of the First-year Survey. Neurol Med Chir (Tokyo) 60(4):165-190, 2020
 
有賀 正 社会医療法人母恋 理事長、北海道大学 名誉教授
小児科学、原発性免疫不全症、遺伝子治療、臨床遺伝学
Okura Y, Kobayashi I, Yamada M, Sasaki S, Yamada Y, Kamioka I, Kanai R, Takahashi Y, Ariga T. Clinical characteristics and genotype-phenotype correlations in C3 deficiency. J Allergy Clin Immunol. 2016 Feb;137(2):640-644.
Cho K, Yamada M, Agematsu K, Kanegane H, Miyake N, Ueki M, Akimoto T, Kobayashi M, Ikemoto S, Tanino M, Fujita A, Hayasaka I, Miyamoto S, Tanaka-Kubota M, Nakata K, Shiina M, Ogata K, Minakami H, Matsumoto N, Ariga T. Heterozygous Mutations in OAS1 Cause Infantile-onset Pulmonary Alveolar Proteinosis with Hypogammaglobulinemia. Am J Hum Genet 102, 480-486, 2018.
Tozawa Y, Nogawa-Chida N, Abdrabou S, Nishiuchi R, Ishida T, Suzuki Y, Sano H, Kobayashi R, Kishimoto K, Ohara O, Imai K, Naruto T, Kobayashi K, Ariga T, Yamada M. A deep intronic mutation of c.1166-285T>G in SLC46A1 is shared by four unrelated Japanese patients with hereditary folate malabsorption (HFM) including one with delayed-onset HFM. Clin Immunol. 2019 Sep 5;208:108256.
 
池田康夫 早稲田大学 特命教授 
慶應義塾大学 名誉教授
血液学
(業績・実績その1)
Kuwana M, Okazaki Y, Ikeda Y.
Detection of circulating B cells producing anti-GPIb autoantibodies in patients with immune thrombocytopenia.
PLoS One. 2014 Jan 22;9(1):e86943. doi: 10.1371/journal.pone.0086943. eCollection 2014.
(業績・実績その2)
Ikeda Y, Shimada K, Teramoto T, Uchiyama S, Yamazaki T, Oikawa S, Sugawara M, Ando K, Murata M, Yokoyama K, Ishizuka N.
Low-dose aspirin for primary prevention of cardiovascular events in Japanese patients 60 years or older with atherosclerotic risk factors: a randomized clinical trial.
JAMA. 2014 Dec 17;312(23):2510-20. doi: 10.1001/jama.2014.15690.
(業績・実績その3)
Platelet production using adipose-derived mesenchymal stem cells: Mechanistic studies and clinical application.
Y Uruga-Ono, Y Ikeda, Y Matsubara,
Journal of Thrombosis & Haemostasis, 2021 Feb, Vol19(2), 342-350.
Cf. First Pub @20 Nov 2020
 
磯部 光章 榊原記念病院 院長・東京医科歯科大学 名誉教授
循環器内科
Isobe M, Yagita H, Okumura K, Ihara A: Specific acceptance of cardiac
allograft after treatment with anti-ICAM-1 and anti-LFA-1. Science, 255:1125-1127, 1992
Isobe M, Maejima Y, Saji M, Tateishi U: Evaluation of tocilizumab for intractable Takayasu arteritis and 18 F-fluorodeoxyglucose-positron emission tomography for detecting inflammation under tocilizumab treatment. J Cardiol 2021 May;77(5):539-544.
Isobe M, Tezuka D: Isolated Cardiac Sarcoidosis: Clinical Characteristics,Diagnosis and Treatment. Int J Cardiol 182: 132-140, 2015.
 
江口 勝美 社会医療法人財団白十字会佐世保中央病院 顧問
リウマチ・膠原病・免疫学
1 Clinical features and human T-cell leukemia virus type-1(HTLV-1)
proviral load in HTLV-1-positive patients with rheumatoid arthritis: Baseline date in a single cohort study.
Eguchi K, Iwanaga M, Terada K, et al. Mod Rheumatol.30(3):471-480, 2020.
2 Rheumatoid arthritis patients with low baseline
Health Assessment Questionnaire scores have a risk of functional disability progression: a post hoc analysis of a nationwide longitudinal cohort in Japan. Sumiyoshi R, Hidaka T, Eguchi K, et al. Cli Exp Rheumatol.38:1096-1101, 2020.
3 Next-generation sequencing of the whole MEFV gene in Japanese patients with familial Mediterranean fever: a case-control association study. Koga T, Sato S, Eguchi K, et al.
Cli Exp Rheumatol.38(Suppl.127): S35-S41,2020.
大澤 真木子 東京女子医科大学 名誉教授
専門分野 小児神経学
Sato T, Murakami T, Ishiguro K, Shichiji M, Saito K, Osawa M, Nagata S, Ishigaki K. Respiratory management of patients with Fukuyama congenital muscular dystrophy. Brain Dev. 2016, 38(3):324-30.
Nationwide survey (incidence, clinical course, prognosis) of Rasmussen's encephalitis.Muto, A., Oguni, H., Takahashi, Y., Shirasaka, Y., Sawaishi, Y., Yano, T., Hoshida, T., Osaka, H., Nakasu, S., Akasaka, N., Sugai, K., Miyamoto, A., Takahashi, S., Suzuki, M., Ohmori, I., Nabatame, S., Osawa, M.:Brain & Dev.2010 32(6);445-53
Hino N, Kobayashi M, Shibata N ,Yamamoto T,Saito K ,Osawa M Clinicopathological study on eyes from cases of Fukuyama type congenital muscular dystrophy. Brain Dev. 2001 23:97-107.
 
片山 一朗 大阪市立大学大学院医学研究科 特任教授
皮膚科学
Morphological Alterations and Increased S100B Expression in Epidermal Langerhans Cells Detected in Skin from Patients with Progressive Vitiligo.Yang F, Yang L, Teng L, Zhang H, Katayama I.Life(Basel).11(6)579. 2021
Local Epidermal Endocrine Estrogen Protects Human Melanocytes against Oxidative Stress, a Novel Insight into Vitiligo Pathology. Yamamoto A, Yang L, Kuroda Y, Guo J, Teng L, Tsuruta D, Katayama I. Int J Mol Sci. 22(1)269. 2020
6-Shogaol Protects Human Melanocytes against Oxidative Stress through Activation of the Nrf2-Antioxidant Response Element Signaling Pathway. Yang L, Yang F, Teng L, Katayama I. Int J Mol Sci.21(10)3537. 2020
 
加藤 義治 東京女子医科大学整形外科 前教授・講座主任
整形外科学 運動器学
研究論文 Katoh Y. Effects of Ethane-1-hydroxy-1,1-diphospho-nate on cell differentiation, and proteoglycan and calcium metabolism in the proximal tibia of young rats. Bone.12: 59-65、1991
「CKD・透析に併発する運動器疾患」 加藤 義治、稲葉 雅章 編, 加藤 義治, 透析と骨関節障害の病態と治療、108-120, 透析患者の椎体骨折, 195-209, 医薬ジャーナル社, 2018
Itoh Tatsuo,Kato Yoshiharu:Posterior decompression for cervical ossfication of the posterior longitudinal ligament.「Ossification of the Posterior Longitudinal Ligament」(Yonenobu K, Sako T, Ono K eds)Springer,Tokyo:pp218@143-152,1997
葛原茂樹 鈴鹿医療科学大学大学院医療研究科長、看護学部看護学科教授
専門分野:神経内科学、難病医療
<研究論文>
Familial amyotrophic lateral sclerosis and parkinsonism-dementia complex of the Kii peninsula of Japan: clinical and neuropathological study and tau analysis. Kuzuhara S, Kokubo Y, Sasaki R, Narita Y, Yabana T, Hasegawa M, Iwatsubo T. Ann Neurol. 2001; 50: 150-156.
<著作>
「わが国における難病対策制度の歴史的展開 (全てが分かる神経難病医療.辻 省次、西澤正豊 編)」葛原茂樹 著, 中山書店, (2015) p8-24.
<著作>
Amyotrophic lateral sclerosis-pakinsonism-dementia complex in the Kii peninsula of Japan (Muro disease): a review on recent research and new concept, Kuzuhara S, Kokubo Y, In: Amyotrophic Lateral Sclerosis and the Frontotemporal Dementias, Edited by Michael J. Strong, Oxford University Press, Oxford, 2012:p39-54.
 
黒岩 義之 財務省診療所長、横浜市立大学名誉教授
脳神経内科学
Toh T, Urata R, Nakawatase A, Yamazaki T, Kuroiwa Y, Baba Y, Fujino K, Kurokawa T: Sensor-level- and ECDL-based brain functional connectivity networks using scalp-recorded EEGs: A comparison of AD and FTD patients and healthy subjects. Computational Neuroscience 9(2):38-44, 2016.
Kimura K, Inoue KI, Kuroiwa Y, Tanaka F, Takada M: Propagated but topologically distributed forebrain neurons expressing alpha-synuclein in aged macaques. Plos one 11(11):e0166861. Nov.2016.
doi:10.1371/journal.pone. 0166861
Omoto S, Kuroiwa Y, Fujino S, Fujino K, Kurokawa T, Baba Y: Greater N1 potential during centrifugal saccades as compared to centripetal saccades in humans: A scalp-recorded electroencephalographic study. The Autonomic Nervous System (Journal of the Japan Society of Neurovegetative Research),54(4):306-315, Dec. 2017.
 
澤倫太郎 日本医師会総合政策研究機構 主任研究員
胎児生理学、産科学、医療経済学
Sawa R, Asakura H, Power GG.
Changes in plasma adenosine during simulated birth of fetal sheep.
J Appl Physiol 70(4): 1524-1528, 1991
Sawa R, Yoneyama Y, Otsubo Y, Suzuki S, Kubonoya K, Power GG, Araki T.
Fetal plasma hypoxanthine level in growth-retarded fetuses before labor.
J Clin Endocrinol Metab 82: 4028-4033, 1997
Ishihara O, Seung Chik Jwa, Kuwabara A, Ishikawa T, Kugu K, Sawa R, Banno K,Saito H
Assisted reproductive technology inJapan: a summary report for 2016
by the Ethics committee of the Japan society of obstetrics and gynecology. Reprod Med Biol.1-10,2018
 
清野 裕 関西電力病院 総長
糖尿病学、内分泌代謝学
Dose-response, efficacy, and safety of oral semaglutide monotherapy in Japanese patients with type 2 diabetes(PIONEER 9):a 52-week, phase 2/3a, randomised, controlled trial. Yamada Y, Katagiri H, Hamamoto Y, Deenadayalan S, Navarria A, Nishijima K, Seino Y;PIONEER 9 investigators. Lancet Diabetes Endocrinol.
2020May;8(5):377-391.doi:10.1016/S2213-8587(20)30075-9.
Inactivation of the Glucose-Dependent Insulinotropic Polypeptide Receptor Improves Outcomes following Experimental Myocardial Infarction. Ussher JR, Campbell JE, Mulvihill EE, Baggio LL, Bates HE, McLean BA, Gopal K, Capozzi M, Yusta B, Cao X, Ali S, Kim M, Kabir MG, Seino Y, Suzuki J, Drucker DJ. Cell Metab. 2018 Feb 6;27(2):450-460.e6. doi: 10.1016/j.cmet. 2017.11.003. Epub 2017 Dec 21.
Stromal cell-derived factor-1 is upregulated by dipeptidyl peptidase-4 inhibition and has protective roles in progressive diabetic nephropathy. Takashima S, Fujita H, Fujishima H, Shimizu T, Sato T, Morii T, Tsukiyama K, Narita T, Takahashi T, Drucker DJ, Seino Y, Yamada Y. Kidney Int. 2016 Oct;90(4):783-96. doi: 10.1016/j.kint. 2016.06.012. Epub 2016 Jul 27.
 
竹中 洋 京都府立医科大学 学長
耳鼻咽喉科学
Enhanced human IgE production results from exposure to the aromaticHydrocarbons from diesel exhaust;direct effects on B-cell IgE production, Takenaka H,et al
J Allery CLin Immunol;1998.95:103-115.
コア・ローテイション 耳鼻咽喉科・頭頸部外科
編集 竹中洋、高橋姿、久育男
金芳堂、2004年1月5日
気道アレルギーの成立とその制御:竹中 洋
第110回日本耳鼻咽喉科学術総会宿題報告
東京、2009.05.14.
 
富野 康日己 医療法人社団松和会 理事長
順天堂大学 名誉教授
腎臓内科学
“Novel coronavirus disease in patients with end-stage kidney disease” Noriaki Shimada, Hiroaki Shimada, Yoshiaki Itaya, Yasuhiko Tomino. Therapeutic Apheresis and Dialysis 11 October 2020 DOI: 10.1111/1744-9987.13599
“Recent Understanding of Peritoneal Pathology in Peritoneal Dialysis Patients in Japan” Chieko Hamada, Yasuhiko Tomino.
Blood Purification, 2021 Feb 10; 1-10 DOI: 10.1159/000510282
“Relationship among Left Ventricular Hypertrophy, Cardiovascular
Events, and Preferred Blood Pressure Measurement Timing in
Hemodialysis Patients” Hiroaki Io, Junichiro Nakata, Hiroyuki
Inoshita, Masanori Ishizaka, Yasuhiko Tomino and Yusuke Suzuki.
J. Clin. Med. 2020, 9, 3512; October 30, 2020
DOI: 10.3390/jcm9113512
 
永井正規 埼玉医科大学名誉教授
疫学
Prevalence and Incidence of Polymyositis and Dermatomyositis in Japan. Ohta A, Nagai M, Nishina M, Tomimitsu H, Kohsaka H.Mod Rheumatol 24:477-480, 2013.
A case control study of female systemic lupus erythematosus in Japan
MASAKI NAGAI,TOMIO HIROHATA,YOSHIFUJI MATSUMOTO,HIROSHI HASHIMOTO,MASAKAZU KONDO,KOTARO OZASA,MITSURU MORI,TSUTOMU HASHIMOTO,HIDEAK
I NAKAGAWA,TOSHITAKA OMURA,MASAKI MORI,TAKESHI TOJO,HIROSHI YANAGAWA European Journal of Public Health, Volume 3, Issue 3:172-176, 1992
「新しい疫学」永井正規他共著,日本公衆衛生協会,(1995).
 
貫和敏博 東北大学 名誉教授
呼吸器内科
Gefitinib Alone Versus Gefitinib Plus Chemotherapy for Non-Small-Cell Lung Cancer With Mutated Epidermal Growth Factor Receptor: NEJ009 Study.
Hosomi Y, Morita S, Sugawara S, Kato T, Fukuhara T, Gemma A, Takahashi K, Fujita Y, Harada T, Minato K, Takamura K, Hagiwara K, Kobayashi K, Nukiwa T, Inoue A; North-East Japan Study Group.
J Clin Oncol. 2020 Jan 10;38(2):115-123.
貫和敏博、肺がん. がん生物学イラストレイテッド、第2版、渋谷正史・湯浅保仁編集、羊土社、2019.
Safety and pharmacokinetics of Alpha-1 MP (Prolastin?-C) in Japanese patients with alpha1-antitrypsin (AAT) deficiency.
Seyama K, Nukiwa T, Sato T, Suzuki M, Konno S, Takahashi K, Nishimura M, Steinmann K, Sorrells S, Chen J, Hayashi KI.
Respir Investig. 2019 Jan;57(1):89-96.
 
日比 紀文 北里大学北里研究所病院 炎症性腸疾患先進治療センター センター長、慶應義塾大学 名誉教授
消化器内科学、消化器免疫学、臨床腫瘍学
Naganuma M, Sugimoto S, Mitsuyama K, Kobayashi T, Yoshimura N, Ohi H, Tanaka S, Andoh A, Ohmiya N, Saigusa K, Yamamoto T, Morohoshi Y, Ichikawa H, Matsuoka K, Hisamatsu T, Watanabe K, Mizuno S, Suda W, Hattori M, Fukuda S, Hirayama A, Abe T, Watanabe M, Hibi T, Suzuki Y, Kanai T; INDIGO Study Group: Efficacy of Indigo Naturalis in a Multicenter Randomized Controlled Trial of Patients With Ulcerative Colitis. Gastroenterology. 154(4):935-947, 2018
Matsuoka K, Kobayashi T, Ueno F, Matsui T, Hirai F, Inoue N, Kato J, Kobayashi K, Kobayashi K, Koganei K, Kunisaki R, Motoya S, Nagahori M, Nakase H, Omata F, Saruta M, Watanabe T, Tanaka T, Kanai T, Noguchi Y, Takahashi KI, Watanabe K, Hibi T, Suzuki Y, Watanabe M, Sugano K, Shimosegawa T: Evidence-based clinical practice guidelines for inflammatory bowel disease. J Gastroenterol. 53(3):305-353,2018
Watanabe K, Matsumoto T, Hisamatsu T, Nakase H, Motoya S, Yoshimura N, Ishida T, Kato S, Nakagawa T, Esaki M, Nagahori M, Matsui T, Naito Y, Kanai T, Suzuki Y, Nojima M, Watanabe M, Hibi T; DIAMOND study group: Clinical and Pharmacokinetic Factors Associated With Adalimumab-Induced Mucosal Healing in Patients With Crohn's Disease. Clin Gastroenterol Hepatol. 16(4):542-549, 2018
 
福島 雅典 京都大学名誉教授
一般財団法人LHS(ラーニングヘルスソサエティー)研究所代表理事
トランスレーションナルリサーチ、臨床試験管理学、腫瘍内科学
COVID-19 pathogenesis, prognostic factors and treatment strategy: urgent recommendations.
Zhou B, Kojima S, Kawamoto A, Fukushima M
J Med Virol 2021 93, 2694
Effect of treating hyperphosphatemia with lanthanium carbonate versus calcium carbonate on cardiovascular events in patients with chronic kidney disease on hemodialysis. The landmark randomized trial.
Ogata H, Fukagawa M Hirakata H Fukushima M AkazawaT LANDMARK Investigator and Committees
JAMA 2021 325 1946
Integrated analysis two Probucol trials for the secondary prevention of atherosclerotic cardiovascular events : prospective and impact
Arai H Bujo H Masuda D et al
J Atheroscler Thromb
2021 28 in press,
http://doi.org/10.5551/jat.62821
 
宮ア 久義 特定非営利活動法人
日本医療マネジメント学会理事長
麻酔、病院管理、地域医療、生活習慣病
癌末期痛に対するモリッカの下垂体破壊術 1.経鼻的下垂体穿刺に必要な基礎的と方法 .宮崎久義,後藤倶子,岡元和文,宇都宮高賢,森岡亨,山室誠,麻酔27:1606-1612.1978
癌末期痛に対するモリッカの下垂体破壊術 2.その成績と作用機序に対する考察 .宮崎久義,後藤倶子,岡元和文,宇都宮高賢,森岡亨,山室誠,麻酔28(1):77-82.1979
Critical Pathway: Practical applications and its development in Japan.Hisayoshi Miyazaki,Teruhiko Matsushima. JMAJ48(11):568-571.2005
 
山下英俊 山形市保健所・保健医療監
眼科学、公衆衛生
Tanaka Y, Katoh S, Hori S, Miura M, and Yamashita H: Vascular endothelial growth factor in diabetic retinopathy. Lancet 349: 1520, 1997
ten Dijke P, Yamashita H, Ichijo H, Franzen P, Laiho M, Miyazono K, and Heldin C-H: Characterization of type I receptors for transforming growth factor-β and activin. Science 264: 101-104, 1994
Nishi K, Nishitsuka K, Yamamoto T, Yamashita H: Factors correlated with visual outcomes at two and four years after vitreous surgery for proliferative diabetic retinopathy. PLOS ONE 2021 Jan 14;16(1):e0244281. doi: 10.1371/journal.pone.0244281. eCollection 2021.

ホーム > 政策について > 分野別の政策一覧 > 他分野の取り組み > 研究事業 > 令和2年度 厚生労働科学研究の概要 > 事前評価委員会名簿 > 難治性疾患政策研究事業事前評価委員名簿

ページの先頭へ戻る