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循環器疾患・糖尿病等生活習慣病対策総合研究事業中間・事後評価委員名簿

(○:委員長)

 
合田 敏尚 静岡県立大学食品栄養科学部教授・副学長
栄養生理学
Self-reported faster eating is positively associated with accumulation of visceral fat in middle-aged apparently healthy Japanese men. Mochizuki K, Yamada M, Miyauchi R, Misaki Y, Kasezawa N, Tohyama K, Goda T. Eur J Nutr. 2014; 53: 1187-1194.
The a-glucosidase inhibitor miglitol decreases glucose fluctuations and inflammatory cytokine gene expression in peripheral leukocytes of Japanese patients with type 2 diabetes. Osonoi T, Saito M, Mochizuki K, Fukaya N, Muramatsu T, Inoue S, Fuchigami M, Goda T. Metabolism 2010; 59: 1816-1822.
Availability, fermentability and energy value of resistant maltodextrin: A modeling of short-term indirect calorimetry measurements in healthy adults. Goda T, Kajiya Y, Suruga K, Tagami H, Livesey G. Am J Clin Nutr. 2006; 83: 1321-1330.
 
川上 康 筑波大学 医学医療系教授
糖尿病、代謝内分泌学
Global and Regional Right Ventricular Function Assessed by Novel Three-Dimensional Speckle-Tracking Echocardiography.
Ishizu T, Seo Y, Atsumi A, Tanaka YO, Yamamoto M, Machino-Ohtsuka T, Horigome H, Aonuma K, Kawakami Y.
J Am Soc Echocardiogr. 2017 Dec;30(12):1203-1213.
Teneligliptin Prevents Cardiomyocyte Hypertrophy, Fibrosis, and Development of Hypertensive Heart Failure in Dahl Salt-Sensitive Rats.
Yamamoto M, Ishizu T, Seo Y, Suto Y, Sai S, Xu D, Murakoshi N, Kimura T, Kawakami Y, Aonuma K.
J Card Fail. 2018 Jan;24(1):53-60.
A candidate functional SNP rs7074440 in TCF7L2 alters gene expression through C-FOS in hepatocytes.
Piao X, Yahagi N, Takeuchi Y, Aita Y, Murayama Y, Sawada Y, Shikama A, Masuda Y, Nishi-Tatsumi M, Kubota M, Izumida Y, Sekiya M, Matsuzaka T, Nakagawa Y, Sugano Y, Iwasaki H, Kobayashi K, Yatoh S, Suzuki H, Yagyu H, Kawakami Y, Shimano H.
FEBS Lett. 2018 Feb;592(3):422-433.
 
齊藤 延人 国立大学法人東京大学・教授
脳神経外科学
Reexpression of developmentally regulated MAP2c mRNA after ischemia: colocalization with hsp72 mRNA in vulnerable neurons. Saito N, Kawai K, and Nowak TS, Jr. J Cereb Blood Flow and Metab 15(2): 205-15, 1995
Experimental model of lacunar infarction in the gyrencephalic brain of the miniature pig - Neurological assessment and histological, immunohistochemical, and physiological evaluation of dynamic corticospinal tract deformation. Tanaka Y, Imai H, Konno K, Miyagishima T, Kubota C, Puentes S, Aoki T, Hata H, Takata K, Yoshimoto Y, and Saito N. Stroke 39(1): 205-212, 2008
Identification of a genetic variant common to moyamoya disease and intracranial major artery stenosis/occlusion. Miyawaki S, Imai H, Takayanagi S, Mukasa A, Nakatomi H, and Saito N. Stroke 43(12): 3371-4, 2012.
 
坂田 隆造 大阪赤十字病院 院長
心臓血管外科学
A therapeutic angiogenesis of sustained release of basic fibroblast growth factor using biodegradable gelatin hydrogel sheets in a canine chronic myocardial infarction model. Kumagai M, Minakata K, Masumoto H, Yamamoto M, Yonezawa A, Ikeda T, Uehara K, Yamazaki K, Ikeda T, Matsubara K, Yokode M, Shimizu A, Tabata Y, Sakata R, Minatoya K. Heart Vessels. 2018 Oct; 33(10): 1251-1257.
Therapeutic angiogenesis by local sustained release of microRNA-126 using poly lactic-co-glycolic acid nanoparticles in murine hind limb ischemia. Tsumaru S, Masumoto H, Minakata K, Izuhara M, Yamazaki K, Ikeda T, Ono K, Sakata R, Minatoya K. J Vasc Surg. 2018 Oct; 68(4): 1209-1215.
Human iPS cell-derived cardiac tissue sheets for functional restoration of infarcted porcine hearts. Ishigami M, Masumoto H, Ikuno T, Aoki T, Kawatou M, Minakata K, Ikeda T, Sakata R, Yamashita JK, Minatoya K. PLoS One. 2018 Aug 2; 13(8): e0201650.
 
代田 浩之 順天堂大学大学院医学研究科循環器内科学・教授
循環器内科学
Clinical indicators and coronary angiographic features of expansive arterial remodelling in patients with abdominal aortic aneurysms.
Endo H, Dohi T, Dohi S, Wada H, Doi S, Kato Y, Okai I, Iwata H, Okazaki S, Isoda K, Yamamoto T, Miyauchi K, Amano A, Daida H.
PLoS One. 2019 Jul 16;14(7):e0219730
The Goal of Achieving Atherosclerotic Plaque Regression with Lipid-Lowering Therapy: Insights from IVUS Trials.
Daida H, Dohi T, Fukushima Y, Ohmura H, Miyauchi K.
J Atheroscler Thromb. 2019 Jul 1;26(7):592-600.
Impact of Lipoprotein (a) Levels on Long-Term Outcomes in Patients With Coronary Artery Disease and Left Ventricular Systolic Dysfunction.
Shitara J, Kasai T, Konishi H, Endo H, Wada H, Doi S, Naito R, Tsuboi S, Ogita M, Dohi T, Okazaki S, Miyauchi K, Daida H.
Circ J. 2019 Apr 25;83(5):1047-1053.
 
中村 好一 自治医科大学 教授
疫学、公衆衛生学、保健統計学
Makino N, Nakamura Y, Yashiro M, Kosami K, Matsubara Y, Ae R, Aoyama Y, Yanagawa H. The nationwide epidemiologic survey of Kawasaki disease in Japan, 2015-2016. Pediatrics International 2019; 61(4): p397-403. doi: 10.1111/ped.13809
柳川洋,中村好一,編.公衆衛生マニュアル 2019 (第37版).東京:南山堂,2019.
中村好一.疫学研究と公衆衛生活動:その基本的な理解(特集:公衆衛生活動と疫学).公衆衛生 2018;82(12):884-888.
 
成松 英智 札幌医科大学医学部救急医学講座・教授
救急医学・集中治療医学・麻酔科学
Narimatsu E, Niiya T, Takada Y, Takahashi K, Yamauchi M, Yamakage M. Blockers of adenosine A1, but not muscarinic acetylcholine, receptors improve excessive extracellular glutamate-induced synaptic depression. Neurosci Res. 2013 Feb;75(2):103-11.
Narimatsu E, Niiya T, Takahashi K, Yamauchi M, Yamakage M. Pralidoxime inhibits paraoxon-induced depression of rocuronium-neuromuscular block in a time-dependent fashion. Am J Emerg Med. 2012 Jul;30(6):901-7.
Narimatsu E, Niiya T, Kawamata T, Kawamata M, Yamakage M. Effects of atropine and pralidoxime on neuronal actions of paraoxon in rat hippocampal slices. Neurosci Res. 2010 Dec;68(4):276-84.
 
籏持 知恵子 大阪府立大学大学院看護学研究科 教授
慢性看護学
急性冠症候群を発症した男性患者の禁煙に関する自己効力感を高めることに焦点をあてた個別禁煙支援プログラムの開発と評価, 戸沢智也,松下由美子,籏持知恵子,日本循環器看護学会誌,12(1),42-50,2016.
慢性心不全患者の浮腫自覚時の受療行動に影響する要因,武田真理,籏持知恵子,日本循環器看護学会誌,11(2), 39-48,2016.
Lifestyle initiatives for glycemic control in young-old patients with diabetes, Seiichiro Masuda, Yae Yabushita, Chieko Hatamochi ,19 th East Asian Forum of Nursing Scholars,2016.
 
早渕 仁美 奈良女子大学生活環境学部 特任教授
公衆栄養学・実践栄養学
「日本人の食事摂取基準(2015年版)」に基づく食事バランスガイド料理区分別サービング数の見直しと検証,早渕仁美, 徳田洋子, 松永泰子, 黒谷佳代, 武見ゆかり.栄養学雑誌, 74(5), 128-140,2016
Circulating ferritin concentrations are differentially associated with serum adipokine concentrations in Japanese men and premenopausal women. Kimura Y, Yasuda K, Kurotani K, Akter S, Kashino I, Hayabuchi H, Sato M, Mizoue T. Eur J Nutr. 2017 Dec;56(8):2497-2505.
「減塩のすべて〜理論から実践まで」日本高血圧学会減塩委員会編集,
 早渕仁美他共著,南江堂(2019)
 
三嶋 理晃 大阪府済生会野江病院院長
呼吸器内科
Mishima M, Hirai T, Itoh H, Nakano Y, Sakai H, Muro S, Nishimura K, Oku Y, Chin K, Ohi M, Nakamura T, Bates JH, Alencar AM, Suki B. Complexity of terminal airspace geometry assessed by lung computed tomography in normal subjects and patients with chronic obstructive pulmonary disease. Proc Natl Acad Sci U S A. 1999; 96(16): 8829-34.
Setoh K, Terao C, Muro S, Kawaguchi T, Tabara Y, Takahashi M, Nakayama T, Kosugi S, Sekine A, Yamada R, Mishima M, Matsuda F. Three missense variants of metabolic syndrome-related genes are associated with alpha-1 antitrypsin levels. Nat Commun. 2015; 6: 7754.
Yamamoto Y, Gotoh S, Korogi Y, Seki M, Konishi S, Ikeo S, Sone N, Nagasaki T, Matsumoto H, Muro S, Ito I, Hirai T, Kohno T, Suzuki Y, Mishima M.Long-term expansion of alveolar stem cells derived from human iPS cells in organoids. Nat Methods. 2017; 14(11): 1097-1106.
水澤 英洋 国立研究開発法人国立精神・神経医療研究センター・理事長
神経内科学
Structural connectivity in spatial attention network: reconstruction from left hemispatial neglect. Hattori T, Ito K, Nakazawa C, Numasawa Y, Watanabe M, Aoki S, Mizusawa H, Ishiai S, Yokota T. Brain Imaging Behav. 2018 April;12(2):309-323.
Analysis of risk factors for mild cognitive impairment based on word list memory test results and questionnaire responses in healthy Japanese individuals registered in an online database. Ogawa M, Sone D, Maruo K, Shimada H, Suzuki K, Watanabe H, Matsuda H, Mizusawa H. PLoS One. 2018 May 17;13(5): e0197466.
Tyrosol Reduces Amyloid-β Oligomer Neurotoxicity and Alleviates Synaptic, Oxidative, and Cognitive Disturbances in Alzheimer's Disease Model Mice. Taniguchi K, Yamamoto F, Arai T, Yang J, Sakai Y, Itoh M, Mamada N, Sekiguchi M, Yamada D, Saitoh A, Kametani F, Tamaoka A, Araki YM, Wada K, Mizusawa H, Araki W. J Alzheimers Dis. 2019; [Epub ahead of print]
 
安井 利一 明海大学・学長
口腔衛生学、健康科学、公衆衛生学
スタンダード衛生・公衆衛生(第16版)・安井利一 他・学建書院・2019年
生活と健康 −測定と評価法−(第5版)・安井利一 他・学建書院・2016年
MAPKs,activator protein-1 and nuclear factor-kappa β mediate of interleukin-1B-stimmulated cytokinase,prostaglandinE2 and MMP-1 human periodontal ligament; Murayama R、Kobayashi M、Takeshita A、Yasui T、and Yamamoto M.J Periodontal Res 46(5): 568-568,2011
 
横山 啓太郎 慈恵医大晴海トリトンクリニック所長
慢性腎臓病、高血圧
Randomised clinical trial of ferric citrate hydrate on anaemia management in haemodialysis patients with hyperphosphataemia: ASTRIO study. Yokoyama K, Fukagawa M, Akiba T, Nakayama M, Ito K, Hanaki K, Wolf M, Hirakata H.
Sci Rep. 2019 Jun 20;9(1):8877.
Long-Term Efficacy and Safety of Evocalcet in Japanese Patients with Secondary Hyperparathyroidism Receiving Hemodialysis.
Yokoyama K, Shimazaki R, Fukagawa M, Akizawa T; Evocalcet Study Group.
Sci Rep. 2019 Apr 23;9(1):6410.
「健康をマネージメントする」横山啓太郎 単著, C.C.C.メディアハウス, (2019).
Effect of Ferric Citrate Hydrate on Fibroblast Growth Factor 23 and Serum Alpha-Klotho in Hemodialysis Patients with Hyperphosphatemia, under Serum Phosphate Level was maintained: ASTRIO Study, Supplementary Analysis. Yokoyama K. Fukagawa M, AkibaT, Nakayama M, Hanaki K, Kyoko I, Hirakata H N. American Society of Nephrology Kidney Week New Orleans. 2018 Nov. (J Am Soc Nephrol.掲載)

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