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肝炎等克服政策研究事業事前評価委員名簿(平成27年度)

(○:委員長)

宮村 達男 国立感染症研究所・名誉所員
ウイルス学
An assay for circulating antibodies to a major etiologic virus of human non-A, non-B hepatitis. Kuo,G., Choo,Q-L., Alter,H.J., Gitnick,G.L., Redeker,A.G., Purcell,R.H., Miyamura,T. Dienstag J.L., Alter,M.J., Stevens,C.E., Tegtmeier,G.E., Bonino,F., Colombo,M., Lee,W-S., Kuo,C., Berger,K., Shuster,J.R., Overby,L.R., Bradley,D.W., and Houghton,M. Science 244: 362-364, 1989.
Detection of antibody against antigen expressed by molecularly cloned hepatitis C virus cDNA: Application to diagnosis and blood screening for post transfusion hepatitis. Miyamura,T., Saito,I., Katayama,T., Kikuchi,S., Tateda,A., Houghton,M., Choo,Q-L., and Kuo,G. Proc.Natl.Acad.Sci.USA, 87: 983-987, 1990.
A cDNA fragment of hepatitis C virus isolated from an implicated donor of post-transfusion non-A, non-B hepatitis in Japan. Kubo,Y., Takeuchi,K., Boonmar,S., Katayama,T., Choo,Q-L., Kuo,G., Weiner,A.W., Bradley,D.W., Houghton,M., Saito,I., and Miyamura,T.  Nucl.Acids Res. 17:10367-10372, 1989.
 
井廻 道夫 新百合ヶ丘総合病院消化器・肝臓病研究所・所長
肝臓病学
Perforin, Fas/Fas ligand, TNF-a pathways as specific and bystander killing mechanisms of hepatitis C virus-specific human CTL. Ando K, Hiroishi K, Kaneko T, Moriyama T, Muto Y, Kayagaki N, Yagita H, Okumura K, Imawari M. J Immunol 1997;158:5283-5291.
Strong CD8+ T-cell responses against tumor-associated antigens prolong the recurrence-free interval after tumor treatment in patients with hepatocellular carcinoma. Hiroishi K, Eguchi J, Baba T, Shimazaki T, Ishii S, Hiraide A, Sasaki M, Doi H, Uozumi S, Omori R, Matsumura T, Yanagawa T, Ito T, Imawari M. J Gastroenterol 2010;45:451-458.
25-hydroxyvitamin D3 suppresses hepatitis C virus production. Matsumura T, Kato T, Sugiyama N, Tasaka-Fujita M, Murayama A, Masaki T, Wakita T, Imawari M. Hepatology 2012;56:1231-1239.
 
遠藤 弘良 東京女子医科大学国際環境・熱帯医学講座・主任教授
国際保健、熱帯医学
S.Miyano,G.Syakantu, K.Komada, H.Endo, T.Sugishita, Cost-effectiveness analysis of the national decentralization policy of antiretroviral treatment programme in Zambia, Cost Effectiveness and Resource Allocation, 2017, 15:4,
W.Paoin, M.Yuenyongsuwan, Y.Yokobori, H.Endo, S.Kim, Development of the ICD-10 simplified version and field test, Professional practice and innovation, 2017
最新保健学講座7 保健医療福祉行政論、(編集)野村陽子、メヂカルフレンド社、2015年、分担題目「感染症に関する主な法律と制度」
 
恩地 森一 済生会今治医療福祉センター・センター長
消化器内科学
Onji M,Autoimmune Hepatitis Study Group. Proposal of autoimmune hepatitis presenting with acute hepatitis, severe hepatitis and acute liver failure. Hepatol Res 2011; 41: 497
S chen, SMF Akbar, M Abe, Y Hiasa, and M Onji: Immunosuppressive functions of hepatic myeloid-derived suppressor cells of normal mice and in a murine model of chronic hepatitis B virus. Clin Exp immunol.2011 Oct; 166(1): 134-142
栄養免疫学への挑戦 恩地森一 日本病態栄養学会誌20(1): 101-109, 2017
 
清澤 研道 社会医療法人城西医療財団城西病院・院長
消化器病・肝臓病・ウイルス肝炎
Kimura T, Kobayashi A, Tanaka N, Sano K, Komatsu M, Fujimori N, Yamazaki T, Shibata S, Ichikawa Y, Joshita S, Umemura T, Matsumoto A, Horiuchi A, Mori H, Wada S, Kiyosawa K, Miyagawa S, Tanaka E.

Clinicopathological characteristics of non-B non-C hepatocellular carcinoma without past hepatitis B virus infection.

Hepatol Res. 2017 Apr;47(5):405-418.
Yoshizawa K, Matsumoto A, Ichijo T, Umemura T, Joshita S, Komatsu M, Tanaka N, Tanaka E, Ota M, Katsuyama Y, Kiyosawa K, Abe M, Onji M.  Long-term outcome of japanese patients with type 1 autoimmune hepatitis. Hepatology 2012 Aug;56(2):668-76
Kiyosawa K, Sodeyama T, Tanaka E, Gibo Y, Yoshizawa K, Nakano Y, Furuta S, Akahane Y, Nishioka K, Purcell RH, et al.: Interrelationship of blood transfusion, non-A, non-B hepatitis and hepatocellular carcinoma: analysis by detection of antibody to hepatitis C virus. Hepatology 1990;12: 671-675.
 
戸田 剛太郎 東京慈恵会医科大学・客員教授
内科学(消化器・肝臓病学)
A large-scale, double-blind trial of ursodoxycholic acid in patients eith chronic hepatitis C.
Omata M, Yoshida H, Toyota J, Tomita E, Nishiguchi S, Hayashi N, Iino S, Makino I, Okita K, Toda G, Tanikawa K, Kumada H; Japanese C-Viral Hepatitis Network
Gut 56:1747-53.2007
Antitumor activity mediated by CD4+ cytotoxic T lymphocyte against MHC class II-negative mouse hepatocellular carcinoma induced by dendritic cell vaccine and interleukin-12.
Homma S, Komita H, Sagawa Y, Ohno T, Toda G
Immunology 115:451-61,2005
Analysis of factors affecting the appearance of hepatocellular carcinoma in patients with chronic hepatitis C. A long term follow-up study after histologic diagnosis.
Aizawa Y, Shibamoto Y, Takagi Y, Zeniya M, Toda G
Cancer 89:53-9,2000
 
矢野 右人 独立行政法人国立病院機構長崎医療センター・名誉院長
ウイルス性肝炎
Quantitative immunoelectrophoresis as a method for determination of hepatitis B antigen
Standardization and comparison with other methods
M. Yano and I. Tripatzis    Z.Immun.-Forsch Bd. 146 : S174-186, 1973.
Prevention of HBV Mother-Infant Transmission
Michitami Yano, Heiichiro Tajim  Acta Paediatrica Japonica 28 (3) : 300-305, 1986
The Long-term Pathological Evolution of Chronic Hepatitis C
Michitami Yano, Hiromitsu Kumada, Masayoshi Kage, Kenji Ikeda, Kazuhide Shimamatsu, Osami Inoue, Etsuko Hashimoto, Jay H. Lefkowitch, Jurgen Ludwig and Kunio Okuda
HEPATOLOGY 23 (6) : 1334-1340, 1996.6
 
吉澤 浩司 広島大学・名誉教授
ウイルス肝炎の疫学
Natural histories of hepatitis C virus infection in men and women simulated by the Markov model. Tanaka J. Kumada H. Ikeda K. Mizui M. Hino K. Katayama K. kumagai J. Kamiya Y . Miyakawa Y. Yoshizawa H. J.Med.Virol.2003,70.378-386.
Livir disease in hepatitis C vinus carriers identified at blood donation and their outcomes with or without interferon treatment:Study on 1019 carriers followed for 5-10 years. Mizui M. Yokoyama T. Tsuji K. Arataki K. Yamaguchi S. Miura T. Kitamoto M. Takezaki E. Orimen S. Sakata T. Kamada K. Maruhashi A. Tamura T. Nakamura T. Ishida K. Teramen K. Miyakawa Y. Yoshizawa H. Hepatology Reserch 2007,37.994-1001.
Minimum infectious dose of hepatitis B virus in chimpanzees and difference in dynamics of viremia between genotype A and genotype C. Komiya Y. Katayama K. Yugi H. Mizui M. Matsukura H. Tomoguri T. Miyakawa Y. Tabuchi A. Tanaka J. Yoshizawa H. Transfusion. 2008,48.286-294.

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