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平成27年度 がん対策推進総合研究事業 事前評価委員名簿

(○:委員長)

 
上田 龍三 愛知医科大学・教授
腫瘍免疫
Phase Ia Study of FoxP3+ CD4 Treg Depletion by Infusion of a Humanized Anti-CCR4 Antibody, KW-0761, in Cancer Patients. Kurose K, Ohue Y, Wada H, Iida S, Ishida T, Kojima T, Doi T, Suzuki S, Isobe M, Funakoshi T, Kakimi K, Nishikawa H, Udono H, Oka M, Ueda R, Nakayama E. Clin Cancer Res.?2015?Oct 1;21(19):4327-36.
Monitoring of Hepatitis B Virus (HBV) DNA and Risk of HBV Reactivation in B-Cell Lymphoma: A Prospective Observational Study. Kusumoto S, Tanaka Y, Suzuki R, Watanabe T, Nakata M, Takasaki H, Fukushima N, Fukushima T, Moriuchi Y, Itoh K, Nosaka K, Choi I, Sawa M, Okamoto R, Tsujimura H, Uchida T, Suzuki S, Okamoto M, Takahashi T, Sugiura I, Onishi Y, Kohri M, Yoshida S, Sakai R, Kojima M, Takahashi H, Tomita A, Maruyama D, Atsuta Y, Tanaka E, Suzuki T, Kinoshita T, Ogura M, Mizokami M, Ueda R. Clin Infect Dis.??2015?Sep. 1;61(5):719-29.
Prognostic significance of tryptophan catabolism in adult T-cell leukemia/lymphoma. Masaki A, Ishida T, Maeda Y, Suzuki S, Ito A, Takino H, Ogura H, Totani H, Yoshida T, Kinoshita S, Narita T, Ri M, Kusumoto S, Inagaki A, Komatsu H, Niimi A, Ueda R, Utsunomiya A, Inagaki H, Iida S. Clin Cancer Res.?2015?Jun. 15;21(12):2830-9.
 
北川 雄光 慶應義塾大学外科学教授
外科
Low DE, Alderson D, Cecconello I, Chang AC, Darling GE, D?Journo XB, Griffin SM, Holscher AH, Hofstetter WL, Jobe BA, Kitagawa Y, Kucharczuk JC, Law SY, Lerut TE, Maynard N, Pera M, Peters JH, Pramesh CS, Reynolds JV, Smithers BM, van Lanschot JJ. International Consensus on Standardization of Data Collection for Complications Associated With Esophagectomy: Esophagectomy Complications Consensus Group (ECCG). Ann Surg 262(2): 286-94, 2015.08
Goto O, Takeuchi H, Kawakubo H, Matsuda S, Kato F, Sasaki M, Fujimoto A, Ochiai Y, Horii J, Uraoka T, Kitagawa Y, Yahagi N. Feasibility of non-exposed endoscopic wall-inversion surgery with sentinel node basin dissection as a new surgical method for early gastric cancer: a porcine survival study. Gastric Cancer 18(2): 440-445, 2015.04
Nagayama A, Hayashida T, Jinno H, Takahashi M, Kitagawa Y. Response. JNCI-J Natl Cancer Inst 107(4): djv039, 2015.03
 
小西 郁生 京都大学大学院医学研究科 婦人科学産科学・教授
産科婦人科学(婦人科腫瘍学)
Peng J, Hamanishi J, Matsumura N, Abiko K, Murat K, Baba T, Yamaguchi K, Horikawa N, Hosoe Y, Murphy SK, Konishi I, Mandai M: Chemotherapy induces programmed cell death-ligand-1 overexpression via the nuclear factor-κB to foster an immunosuppressive tumor microenvironment in ovarian cancer. Cancer Res 75:5034-5045, 2015
Abiko K, Matsumura N, Hamanishi J, Horikawa N, Murakami R, Yamaguchi K, Yoshioka Y, Baba T, Konishi I, Mandai M: IFN-γ from lymphocytes induces PD-L1 expression and promotes progression of ovarian cancer. Br J Cancer 112:1501-1509, 2015
Amano Y, Mandai M, Yamaguchi K, Matsumura N, Kharma B, Baba T, Abiko K, Hamanishi J, Yoshioka Y, Konishi I: Metabolic alterations caused by HNF1β expression in ovarian clear cell carcinoma contribute to cell survival. Oncotarget 6:26002-26017, 2015
 
小松 浩子 慶應義塾大学看護医療学部・学部長・教授
看護学
Komatsu H, Yagasaki K, Yamauchi H, Yamauchi T. Patients' Perspectives on Creating a Personal Safety Net During Chemotherapy. Clin J Oncol Nurs. 2016 Feb;20(1):13-6. doi: 10.1188/16.CJON.13-16.
Yagasaki K, Komatsu H, Takahashi T. Inner conflict in patients receiving oral anticancer agents: a qualitative study. BMJ Open. 2015 Apr 14;5(4):e006699. doi: 10.1136/bmjopen-2014-006699.
Komatsu H, Yagasaki K. The power of nursing: guiding patients through a journey of uncertainty. Eur J Oncol Nurs. 2014.18(4), 419-24.
 
関原 健夫 日本対がん協会常務理事
専門分野
闘病記「がん六回 人生前回」(朝日新聞社:講談社:ブックマン社)
 
祖父江 友孝 大阪大学大学院医学系研究科・教授
専門分野
Sobue T, Suzuki T, Naruke T. A case-control study for evaluating lung-cancer screening in Japan. Int J Cancer, 50: 230-7, 1992
Sobue T, Moriyama N, Kaneko M, Kusumoto M, Kobayashi T, Tsuchiya R, Kakinuma R, Ohmatsu H, Nagai K, Nishiyama H, Matsui E, Eguchi K. Screening for lung cancer with low-dose helical computed tomography: Anti-Lung Cancer Association Project. J Clin Oncol, 20: 911-20, 2002.
Sobue T, Yamamoto S, Hara M, Sasazuki S, Sasaki S, Tsugane S, JPHC Study Group. Japanese Public Health Center. Cigarette smoking and subsequent risk of lung cancer by histologic type in middle-aged Japanese men and women: the JPHC study. Int. J. Cancer, 99: 245-251, 2002.
 
原 純一 大阪市立総合医療センター副院長
小児血液腫瘍学
Development of treatment strategies for advanced neuroblastoma. Hara J. Int J Clin Oncol. 2012 Jun;17(3):196-203.?
Double-conditioning regimens consisting of thiotepa, melphalan and busulfan with stem cell rescue for the treatment of pediatric solid tumors. Hara J, Osugi Y, Ohta H, Matsuda Y, Nakanishi K, Takai K, Fujisaki H, Tokimasa S, Fukuzawa M, Okada A, Okada S.Bone Marrow Transplant. 1998 Jul;22(1):7-12.
Comparison of T cell receptor alpha, beta, and gamma gene rearrangement and expression in T cell acute lymphoblastic leukemia. Hara J, Benedict SH, Champagne E, Mak TW, Minden M, Gelfand EW.
J Clin Invest. 1988 Apr;81(4):989-96.
 
堀田 知光 国立がん研究センター・理事長
専門分野
Phase I/II study of bortezomib-merphalan-prednisolone for previously untreated Japanese patients with multiple myeloma. Uchida T, Suzuki K, Sakai A, Iida S, Hotta T. Cancer Sci. 104(7), 912-919, 2013
Phase II/III study of R-CHOP-21 versus R-CHOP-14 for untreated indolent B-cell non-Hodgkin’s lymphoma: JCOG 0203 trial. Watanabe T, Tobinai K, Shibata T, Tsuksaki K,MorishimaY, Hotta T: J Clin Oncol 29(30) 3990-3998, 2011
Phase III trial of CHOP-21 versus CHOP-14 for aggressive non-Hodgkin’s lymphoma: final results of the Japan Clinical Oncology Group study, JCOG 9809. Ohmachi K, Tobinai K, Kobayashi K, Itoh K, Nakata M, Shibata T, Hotta T. Ann Oncol 22, 1382-1391, 2011
門田 守人 地方独立行政法人堺市立病院機構 理事長
消化器外科
Operative morbidity of living liver donors in Japan.
Umeshita K, Fujiwara K, Kiyosawa K, Makuuchi M, Satomi S, Sugimachi K, Tanaka K, Monden M;. Lancet. 2003 Aug 30;362(9385):687-90.
Differential transcriptome patterns for acute cellular rejection in recipients with recurrent hepatitis C after liver transplantation.
Asaoka T, Kato T, Marubashi S, Dono K, Hama N, Takahashi H, Kobayashi S, Takeda Y, Takemasa I, Nagano H, Yoshida H, Ruiz P, Tzakis AG, Matsubara K, Monden M, Doki Y, Mori M.
Liver Transpl. 2009 Dec;15(12):1738-49.
Evolution of registry and tracking system for organ transplantation in Japan.
Yuzawa K, Takahara S, Kanmochi T, Takahashio K, Umeshita H, Monden M, Teraoka S. Transplant Proc. 2012 May;44(4):828-31.

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