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稲垣 治 |
日本製薬工業協会 医薬品評価委員会 委員長 |
| 医薬品開発 |
治験の空洞化を防ぐための早期探索的臨床試験の推進 −企業の立場から−
稲垣 治
Jpn. J. Clin Pharmacol. Ther., 42(2), 85-86 (2011)
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内海 英雄 |
九州大学先端融合医療レドックスナビ研究拠点・特任教授 |
| 物理薬学 |
Simultaneous and spectroscopic redox molecular imaging of multiple free radical intermediates using dynamic nuclear polarization-magnetic resonance imaging., Hyodo, F., Ito, S., Yasukawa, K., Kobayashi, R., & Utsumi, H. Anal Chem, 86 (15), 7234-7238. (2014)
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| Whole-body kinetic image of a redox probe in mice using Overhauser-enhancesd MRI., Kosem N., Naganuma T., Ichikawa K., Morales N. P., Yasukawa K., Hyodo F., Yamada KI., Utsumi H., Free Radic Biol Med., 53:328-336, 2012 |
| Minocycline modulates human social decision-making: possible impact of microglia on personality-oriented social behaviors. Kato TA, Watabe M, Tsuboi S, Ishikawa K, Hashiya K, Monji A, Utsumi H, Kanba S., PLoS One; 7(7):e40461., (2012) |
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大野 泰雄 |
木原記念横浜生命科学振興財団 理事長 |
| トキシコロジー |
| Open TG-GATEs: a large-scale toxicogenomics database. Igarashi Y, Nakatsu N, Yamashita T, Ono A, Ohno Y, Urushidani T, Yamada H., Nucleic Acids Res. 2015 Jan 28;43(Database issue):D921-7. |
| miRNA expression atlas in male rat. Keiichi Minami, Uehara T, Morikawa Y, Omura K, Kanki M, Horinouchi A, Ono A, Yamada H, Ohno Y and Urushidani T, Nature SCIENTIFIC DATA | 1:140005 | DOI: 10.1038/sdata.2014.5 |
| Intra-/inter-laboratory validation study on reactive oxygen species assay for chemical photosafety evaluation using two different solar simulators. Onoue S, Hosoi K, Toda T, Takagi H, Osaki N, Matsumoto Y, Kawakami S, Shinobu Wakuri S, Iwase Y, Yamamoto T, Nakamura K, Ohno Y, and Kojima H, Toxicol In Vitro. 28: 515-23, 2014. |
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高坂 新一 |
国立精神・神経医療研究センター
神経研究所長 |
| 神経化学 |
Takezawa Y, Kohsaka S, Nakajima K.:
Transient down-regulation and restoration of glycogen synthase levels in axotomized rat facial motoneurons.
Brain Res. 1586 (2014) 34-45.
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Gonda Y, Andrews W. D, Tabata H, Namba T, Parnavelas J. G, Nakajima K, Kohsaka S, Hanashima C, Uchino S.:
Robo1 Regulates the Migration and Laminar Distribution of Upper-Layer Pyramidal Neurons of the Cerebral Cortex.
Cerebral Cortex 23 (2013) 1495-1508.
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Ohsawa K, Sanagi T, Nakamura Y, Suzuki E, Inoue K, Kohsaka S.:
Adenosine A3 receptor is involved in ADP-induced microglial process extension and migration.
J Neurochem. 121 (2012) 217-227.
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佐竹元吉 |
お茶の水女子大学 生活環境教育研究センター
客員教授 |
| 専門分野：薬用植物学 |
| 日本の有毒植物 株）学研教育出版(2012年 5月) |
| Hiroyuki Fuchino, Fumiyuki Kikuchi, Azusa Yamanaka, Akihiro Obu, Hiroshi Wada, Kanami Mori-Yasumoto, Nobuo Kawahara, Diana Flores, Olga Palacios, Setsuko Sekita, and Motoyoshi Satake, New Leishmanicidal Stilbenes from a Peruvian Folk Medecine, Lonchocarpus nicou : Chem. Pharm. Bull. 61(9)979-982(2013) |
| Kohei Kazuma, Motoyoshi Satake and Katsuhiro Konno, A Case of Fatal Aconite Poisoning and Its Background : 食衛誌Vol.54 No,6 Dec. (2013) |
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田澤 義明 |
一般社団法人 日本臨床検査薬協会 |
| コンパニオン診断薬ワーキング |
| 当該年度は該当なし。 |
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服部 征雄 |
富山大学 監事（非常勤） |
| 薬用植物学 |
| Survey of Anti-HIV and Anti-HCV Compounds from Natural Sources, , Masao Hattori, Chao-Mei Ma, Ying Wei, Riham Salah El Dine, Naoto Sato, Canadian Chemical Transactions（Licensee Borderless Science Publishing, Canada.）, 1, 116-140 (2013). |
漢方薬の薬効には腸内細菌が関与する. 服部征雄,腸内細菌学雑誌,
２６,１５９-１６９ (２０１２).
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Recent studies on peomy roots and a bioactive constituent, paeonifrorin, Meselhy R.Meselhy and Masao Hattori, Current Topics in Phytochemistry, 4, 1-19 (2000).
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布施 英一 |
協和発酵キリン（株） 研究開発本部 トランスレーショナルリサーチユニット ユニット長 |
| 薬用動態 |
| Application of pharmacokinetically guided dose escalation with respect to cell cycle phase specificity, Fuse, E., Kobayashi, S., Inaba, M., Suzuki, H., Sugiyama, Y.: Journal of the National Cancer Institute, 86(13), 989-996 (1994) |
| Unpredicted clinical pharmacology of UCN-01 caused by specific binding to human α1-acid glycoprotein, Fuse, E., Tanii, H., Kurata, N., Kobayashi, H., Shimada, Y., Tamura, T., Sasaki, Y., Tanigawara, Y., Lush, R.D., Headlee, D., Figg, W.D., Arbuck, S.G., Senderowicz, A.M., Sausville, E.A., Akinaga, S., Kuwabara, T., Kobayashi, S.: Cancer Research, 58(15), 3248-3253 (1998) |
| P-glycoprotein limits the brain penetration of olopatadine hydrochloride, H1-receptor antagonist, Mimura, N., Nagata, Y., Kuwabara, T., Kubo, N., Fuse, E.: Drug Metabolism and Pharmacokinetics, 23(2), 106-114 (2008) |
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矢守 隆夫 |
独立行政法人医薬品医療機器総合機構 審査センター長 |
| 分子薬理学 |
JFCR39, a panel of 39 human cancer cell lines, and its application in the discovery and development of anticancer drugs.
Kong D, Yamori T.
Bioorg Med Chem. 20(6) 1947-51 2012年
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AMF-26, a Novel Inhibitor of the Golgi System, Targeting ADP-ribosylation Factor 1 (Arf1) with Potential for Cancer Therapy.
Ohashi Y, Iijima H, Yamaotsu N, Yamazaki K, Sato S, Okamura M, Sugimoto K, Dan S, Hirono S, Yamori T.
J Biol Chem. 287(6) 3885-97 2012年
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Antitumor activity of ZSTK474, a new phosphatidylinositol 3-kinase inhibitor.
Yaguchi S1, Fukui Y, Koshimizu I, Yoshimi H, Matsuno T, Gouda H, Hirono S, Yamazaki K, Yamori T.
J Natl Cancer Inst. 2006 Apr 19;98(8):545-56.
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渡邉 治雄 |
国立感染症研究所 所長 |
| 細菌学 |
| Jeelani G, Sato D, Soga T, Watanabe H, Nozaki T. Mass Spectrometric Analysis of l-Cysteine Metabolism: Physiological Role and Fate of l-Cysteine in the Enteric Protozoan Parasite Entamoeba histolytica. MBio. 4;5(6). doi: 10.1128/mBio.01995-14.2014 |
Munirul Alam, Shah Manzur Rashed, Shahnewaj Bin Mannan, Tarequl Islam, Marcial Leonardo Lizarraga-Partida,Gabriela Delgado, Rosario Morales-Espinosa, Jose Luis Mendez, Armando Navarro, Haruo Watanabe,
Makoto Ohnishi, Nur A. Hasan, Anwar Huqe, R. Bradley Sack, Rita R. Colwelle and Alejandro Cravioto. Occurrence in Mexico, 1998-2008, of Vibrio cholera CTX+ El Tor carrying an additional truncated CTX prophage. Pro.Natl.Acad.Sci.USA. 111(27):9917-9922. 2014
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| Morita-Ishihara T, Miura M, Iyoda S, Izumiya H, Watanabe H, Ohnishi M, Terajima J. EspO1-2 Regulates EspM2-Mediated RhoA Activity to Stabilize Formation of Focal Adhesions in Enterohemorrhagic Escherichia coli-Infected Host Cells. PLoS One. 8(2):e55960. 2013 |
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