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宮村 達男 |
国立感染症研究所 名誉所員 |
| ウイルス学 |
| An assay for circulating antibodies to a major etiologic virus of human non-A, non-B hepatitis. Kuo,G., Choo,Q-L., Alter,H.J., Gitnick,G.L., Redeker,A.G., Purcell,R.H., Miyamura,T. Dienstag J.L., Alter,M.J., Stevens,C.E., Tegtmeier,G.E., Bonino,F., Colombo,M., Lee,W-S., Kuo,C., Berger,K., Shuster,J.R., Overby,L.R., Bradley,D.W., and Houghton,M. Science 244: 362-364, 1989. |
| Detection of antibody against antigen expressed by molecularly cloned hepatitis C virus cDNA: Application to diagnosis and blood screening for post transfusion hepatitis. Miyamura,T., Saito,I., Katayama,T., Kikuchi,S., Tateda,A., Houghton,M., Choo,Q-L., and Kuo,G. Proc.Natl.Acad.Sci.USA, 87: 983-987, 1990. |
| A cDNA fragment of hepatitis C virus isolated from an implicated donor of post-transfusion non-A, non-B hepatitis in Japan. Kubo,Y., Takeuchi,K., Boonmar,S., Katayama,T., Choo,Q-L., Kuo,G., Weiner,A.W., Bradley,D.W., Houghton,M., Saito,I., and Miyamura,T. Nucl.Acids Res. 17:10367-10372, 1989. |
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樋野 興夫 |
順天堂大学 医学部 病理・腫瘍学 教授 |
| 専門分野 病理学・発がん |
Hino O., Kitagawa T. and Sugano H.: Relationship between serum and histochemical markers for hepatitis B virus and rate of viral integration in hepatocellular carcinomas in Japan. Int J Cancer 35: 5-10, 1985
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Hino O., Shows T. B. and Rogler C. E.: Hepatitis B virus integration site in hepatocellular carcinoma at chromosome 17;18 translocation. Proc Natl Acad Sci U S A 83: 8338-8342, 1986
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Hino O., Tabata S. and Hotta Y.: Evidence for increased in vitro recombination with insertion of human hepatitis B virus DNA. Proc Natl Acad Sci U S A 88: 9248-9252, 1991
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沖田 極 |
社会保険下関厚生病院名誉院長・顧問 |
| 肝臓病学 |
Furutani T, Hino K, Okita K, et al.:Hepatic iron overload induces hepatocellular carcinoma in transgenic mice expressing the hepatic C virus polyprotein. Gastroenterology 131:461-469,2006
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| Nishina S, Hino K, Okita K, et al.:Hepatitis C virus induced reactive oxygen species raise hepatic iron level in mice by reducing hepcidin transcription. Gastroenterology 134:226-238,2008 |
（発明）
特許第4997377号（登録日：平成24年5月25日）
名称：骨髄細胞の遊走・分化・増殖評価モデル動物およびその利用法
発明者：寺井崇二、沖田 極（特許権者：国立大学法人山口大学）
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倉田 毅 |
国際医療福祉大学塩谷病院中央検査部長 教授 |
| ウイルス感染症の発症病理学 |
Akira Ainai, Shin-ichi Tamura, Tadaki Suzuki, Elly van Riet, Ryo Ito, Takato Odagiri, Masato Tashiro, Takeshi Kurata
and Hideki Hasegawa: Intranasal vaccination with an inactivated whole influenza virus induces strong antibody
resposes in serum and nasal mucus of healthy adults. Human vaccines and Immunotherapeutics 9-9,:1962-1970 , 2013
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Masae Iwai-Itamochi, Hiromu Yoshida,Mayumi Obara-Nagoya, Eiji Horimoto, Takeshi Kurata, Takenori Takizawa:
Development of real-time PCR to detect oral vaccine-like poliovirus and its application to enviromental surveillance.
J.Virological Methods195, 148-155, 2014
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西島 正弘 |
昭和薬科大学・学長 |
| 生化学 |
Molecular machinery for non-vesicular trafficking of ceramide
K. Hanada, K. Kumagai, S. Yasuda, Y. Miura, M. Kawano, M. Fukasawa, and M. Nishijima
Nature (Article), 426, 803-809, 2003
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A Potent Adjuvant Monophosphoryl Lipid A Triggers Various Immune Response, but Not Secretion of lL-1・ or Activation of Caspase-1
K. Okemoto, K. Kawasaki, K. Hanada, M. Miura, and M. Nishijima
J. Immunol., 176, 1203-1208, 2006
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Structural basis for specific lipid recognition by CERT responsible for nonvesicular trafficking of ceramide
N. Kudo, K. Kumagai, N. Tomishige, T. Yamaji, S. Wakatsuki, M. Nishijima, K. Hanada, and R. Kato
Proc. Natl. Acad. Sci.USA., 105, 488-493, 2008
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関谷 剛男 |
公益財団法人佐々木研究所・常務理事 附属佐々木研究所・所長 |
| 核酸化学 |
M. Orita, H. Iwahana, H. Kanazawa, K. Hayashi and T. Sekiya. Detection of polymorphisms of human DNA by gel electrophoresis as single-strand conformation polymorphisms. Proc. Natl. Acad. Sci. USA 86, 2766-2770, 1989
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M. Orita, Y. Suzuki, T. Sekiya and K .Hayashi. Rapid and sensitive detection of point mutation and DNA Polymorphisms using the polymerase chain reaction. Genomics 5, 874-879, 1989
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T. Sekiya. Nucleotide sequence changes in human genome: detection by single-strand conformation polymorphism analysis. Proc. Japan Acad. Ser B, 80, 92-102, 2004
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小池 克郎 |
一般社団法人バイオ医薬研究所・代表理事・所長 |
| B型肝炎ウイルス分子遺伝学 |
| Hepatitis B virus (HBV) particles are produced in a cell culture system by transient expression of transfected HBV DNA. Katsuyuki Yaginuma, Yumiko Shirakata, Midori Kobayashi and Katsuro Koike, Proc. Natl. Acad. Sci. USA 84: 2678-2682, 1987. |
| Trans-activation function of a 3' truncated X gene-cell fusion product from integrated hepatitis B virus DNA in chronic hepatitis tissues. Shinako Takada and Katsuro Koike, Proc. Natl. Acad. Sci. USA 87: 5628-5632, 1990. |
| HBV DNA integration and insertional-mutagenesis (Review). K. Koike in "Hepatitis B Virus: Molecular Mechanisms in Disease and Novel Strategies for Therapy" (R. Koshy and W. H. Caselmann, eds.), pp.133-160, Imperial College Press, London, 1998. |
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山口 一成 |
熊本大学発生医学研究所 特別研究員 |
| 血液学、ウイルス学、ワクチン、感染症 |
| Takizawa K, Nakashima T, Mizukami T, Kuramitsu M, Endoh D, Kawauchi S, Sasaki K, Momose H, Kiba Y, Mizutani T, Furuta RA, Yamaguchi K, Hamaguchi I: Degenerate PCR strategy with DNA microarray for detection of multiple and various subtypes of virus during blood screening. Transfusion 53:2545-2555,2013 |
| Asanuma S, Yamagishi M, Kawanami K, Nakano K, Sato-Otsubo A, Muto S, Sanada M, Yamochi T, Kobayashi S, Utsunomiya A, Iwanaga M, Yamaguchi K, Uchimaru K, Ogawa S, Watanabe T: Adult T-cell leukemia cells are characterized by abnormalities of Helios expression that promote T cell growth. Cancer Sci. 104(8):1097-106. 2013 |
| Ito M, Kusunoki H, Mochida K, Yamaguchi K, Mizuochi T: HCV infection and B-cell lymphomagenesis. Advances in Hematology 10.1155,2011 |
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松原 謙一 |
大阪大学名誉教授 |
| 分子生物学 |
A. Miyanohara, A. Toh-e, C. Nozaki, F. Hamada, N. Ohtomo, K. Matsubara
Expression of hepatitis B surface antigen gene in yeast
Proc. Natl. Acad. Sci. U. S. A. 80 1-5 (1983)
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K. Okubo, N. Hori, R. Mtoba, T. Niiyama, A. Fukushima, Y. Kojima, K. Matsubara
Large scale cDNA sequencing for analysisi of quantitative and qualitative aspects of gene expression
Natur Genetics 1992 Nov: 2:173-9
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