| |
| 大島 悦男 |
協和発酵キリン（株）執行役員、研究本部長 |
| 医薬品化学、有機合成化学、天然物化学 |
Synthesis and Antiallergic Activity of 11-(Aminoalkylidene)-6,11-
dihydrodibenz[b,e]oxepin Derivatives.
Ohshima, E.; Otaki, S.; Sato, H.; Kumazawa, T.; Obase, H.; Ishii, A.; Ishii, H.; Ohmori, K.; Hirayama, N. J. Med. Chem. 1992, 35, 2074-2084. |
Non-prostanoid Thromboxane A2 Receptor Antagonists with a Dibenzoxepin Ring System. 2.
Ohshima, E.; Takami, H.; Sato, H.; Mohri, S.; Obase, H.; Miki, I.; Ishii, A.; Shirakura, S.; Karasawa, A.; Kubo, K. J. Med. Chem. 1992, 35, 3402-3413. |
| Synthesis of 1・-Fluorovitamin D3. Ohshima, E.; Takatsuto, S.; Ikekawa, N.; DeLuca, H. F. Chem. Pharm. Bull. 1984, 32, 3518-3524. |
|
| |
| 倉田 毅 |
国際医療福祉大学塩谷病院中央検査部 部長、教授 |
| ウイルス感染症 |
Akira Ainai, Shin-ichi Tamura, Tadaki Suzuki, Elly van Riet, Ryo Ito, Takato Odagiri, Masato Tashiro, Takeshi Kurata
and Hideki Hasegawa: Intranasal vaccination with an inactivated whole influenza virus induces strong antibody
resposes in serum and nasal mucus of healthy adults. Human vaccines and Immunotherapeutics 9-9,:1962-1970, 2013 |
| |
| |
|
| ○ |
| 高坂 新一 |
国立精神・神経医療研究センター 理事
(兼)神経研究所長 |
| 神経化学 |
Gonda Y, Andrews W. D, Tabata H, Namba T, Parnavelas J. G, Nakajima K, Kohsaka S, Hanashima C, Uchino S.:
Robo1 Regulates the Migration and Laminar Distribution of Upper-Layer Pyramidal Neurons of the Cerebral Cortex.
Cerebral Cortex 23 (2013) 1495-1508. |
Sanagi T, Nakamura Y, Suzuki E, Uchino S, Aoki M, Warita H, Itoyama Y, Kohsaka S, Ohsawa K.:
Involvement of activated microglia in increased vulnerability of motoneurons after facial nerve avulsion in presymptomatic amyotrophic lateral sclerosis model rats.
Glia. 60(2012) 782-793. |
Ohsawa K, Sanagi T, Nakamura Y, Suzuki E, Inoue K, Kohsaka S.:
Adenosine A3 receptor is involved in ADP-induced microglial process extension and migration.
J Neurochem. 121 (2012) 217-227. |
|
| |
| 佐竹元吉 |
お茶の水女子大学 生活環境教育研究センター
客員教授 |
| 専門分野：薬用植物学 |
| 日本の有毒植物 株）学研教育出版(2012年 5月) |
|
Kanami Mori-Yasumoto, Ryoko Izumoto, Hiroyuki Fuchino, Takashi Ooi, Yutaka Agatsuma, Takenori Kusumi, Motoyoshi Satake, Setsuko Sekita, Leishmanicidal activities and cytotoxicities of bisnaphthoquinone analogues and naphthol derivatives from Burman Diospyros burmanica, Bioorganic & Medicinal Chemistry Vol. 20 (2012)5215-5219 |
|
Shin-ichiro Kawada, Kohei Kazuma, Haruka Asahina, Takashi Tsuchida, Noriko Tominaga and Motoyoshi Satake, Insectivorous Small Mammals inNorthern and Middle Myanmar, Mem. Natl. Mus. Nat. Sci., Tokyo (48), pp. 75-80, March 28, 2012 |
|
| |
| 早川 堯夫 |
近畿大学薬学総合研究所 所長 |
| 生物化学、薬学 |
| ヒト幹細胞を用いた細胞・組織加工医薬品等の品質・安全性確保に関する指針整備と主なポイント.（その１）−（その８）．早川堯夫、青井貴之、梅澤明弘、小澤敬也、佐藤陽治、澤 芳樹、松山晃文、大和雅之、山中伸弥、再生医療、10(3), 86-152 (2011) |
| Japanese Regulatory Perspective on Immunogenicity. Detection and Quantification of Antibodies to Biopharmaceuticals : Practical and Applied Considerations (ed. by Michael G. Tovey), Takao Hayakawa and Akiko Ishii: John Wiley & Sons, Inc., New Jersey, USA, August 2011 |
| A Possible Role for Protein Phosphorylation in the Activation of the Respiratory Burst in Human Neutrophils: Evidence from studies with cells from patients with chronic granulomatous disease, T. Hayakawa, K. Suzuki, S. Suzuki, P.C. Andrews and B.M. Babior: J. Biol. Chem., 261(20), 9109-9115 (1986) |
|
|
| 福重 潤一郎 |
第一三共株式会社 研究開発業務部 主査 |
| 実験動物 |
| 悪性腫瘍患者の結核症. 福重潤一郎, 丸山孝一, 川上浩 他, 癌の臨床32: 234〜240, 1986. |
| HMG-CoA還元酵素阻害剤の開発から最新知見まで HMG-CoA還元酵素阻害剤の動物による安全性評価．福重潤一郎, 谷吉朗, Prog Med．1998 May；18（5）：1018-1022. |
| ウサギ腎近位尿細管細胞の初代培養と各種抗生剤の細胞毒性. 水野初枝，福重潤一郎，横山富久，吉田由美子, 日本動物実験代替法学会第 8回大会, 1994 |
|
| |
| 山口 一成 |
熊本大学発生医学研究所 特別研究員 |
| 血液学、ウイルス学、ワクチン、感染症 |
| Takizawa K, Nakashima T, Mizukami T, Kuramitsu M, Endoh D, Kawauchi S, Sasaki K, Momose H, Kiba Y, Mizutani T, Furuta RA, Yamaguchi K, Hamaguchi I: Degenerate PCR strategy with DNA microarray for detection of multiple and various subtypes of virus during blood screening. Transfusion 53:2545-2555,2013 |
| Current prevalence of HTLV-1 in Japan as determinined by screening of blood donors. Satake M, Yamaguchi K, Tadokoro K. J Med Virol 84(2):327-35,2012 |
| HCV infection and B-cell lymphomagenesis. Ito M, Kusunoki H, Mochida K, Yamaguchi K, Mizuochi T: Advances in Hematology 10.1155,2011 |
|
| |
| 山西 弘一 |
医薬基盤研究所 理事長 |
| ウイルス学、ワクチン学 |
Intranasal immunization with a formalin-inactivated human influenza a virus whole-virion vaccine alone and intranasal immunization with a split-virion vaccine with mucosal adjuvants show similar levels of cross-protection.
Okamoto S, Matsuoka S, Takenaka N, Haredy AM, Tanimoto T, Gomi Y, Ishikawa T, Akagi T, Akashi M, Okuno Y, Mori Y, Yamanishi K.
Clin Vaccine Immunol. 19、:979-90. 2012 |
Rapid and efficient introduction of a foreign gene into bacterial artificial chromosome-cloned varicella vaccine by Tn7-mediated site-specific transposition.
Somboonthum P, Koshizuka T, Okamoto S, Matsuura M, Gomi Y, Takahashi M, Yamanishi K, Mori Y.
Virology. 402 :215-21、2010 |
A community-based survey of varicella-zoster virus-specific immune responses in the elderly.
Tang H, Moriishi E, Okamoto S, Okuno Y, Iso H, Asada H, Yamanishi K, Mori Y; for the Shozu Herpes Zoster (SHEZ) Study group.
J Clin Virol. In press 2012 |
|
| |
| 吉木 淳 |
理化学研究所バイオリソースセンター・実験動物開発室長 |
| 実験動物学、動物遺伝学 |
| Mochida, K., Hasegawa, A., Li, M. W., Fray, M. D., Kito, S., Vallelunga, J. M., Lloyd, K. C., Yoshiki, A., Obata, Y. and Ogura, A. High osmolality vitrification: a new method for the simple and temperature-permissive cryopreservation of mouse embryos. PLoS One 8, e49316, 2013. |
| Cao, L., Kobayakawa, S., Yoshiki, A. and Abe, K. High resolution intravital imaging of subcellular structures of mouse abdominal organs using a microstage device. PLoS One 7, e33876, 2012. |
| Kasahara, T., Abe, K., Mekada, K., Yoshiki, A. and Kato, T. Genetic variation of melatonin productivity in laboratory mice under domestication. Proc Natl Acad Sci U S A 107, 6412-6417, 2010. |
|
