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食品の安心・安全確保推進研究事業事前評価委員名簿

(○:委員長)

 
一色 賢司 北海道大学大学院水産科学研究院 教授
食品衛生学
M.L.Bari, Y.Sabina, S.Kawamoto, K.Isshiki, Microbiological Safety and Quality of Processed Shrimps and Fishes, Aquaculture Microbiology and Biotechnology, Volume 2, ed. D.Montet, R.C.Ray, CRC Press, Boca Raton, FL, USA, pp.73-100 (2011)
Regulatory issues in Japan regarding produce safety,“The Produce Contamination Problem: Causes and Solutions”, K.Isshiki, M.L.Bari,  S.Kawamoto, T.Shiina; Edited by G.M.Sapers, , E.B.Solomon, . K.R.Matthews, (Academic Press: San Diego), p.353-392 (2009)
食品安全と食品衛生、一色賢司、小田隆弘、宮本敬久、村田容常、
「食品安全の事典」日本食品衛生学会編、朝倉書店、p.3-41(2009)
門脇 孝 東京大学大学院医学系研究科糖尿病・代謝内科
糖尿病、肥満
Kadowaki T and Yamauchi T: Adiponectin receptor signaling: a new layer to the current model.
Cell Metabolism 13: 123-124, 2011
Iwabu M, Yamauchi T, Okada-Iwabu M, Sato K, Nakagawa T, Funata M, Yamaguchi M, Namiki S, Nakayama R, Tabata M, Ogata H, Kubota N, Takamoto I, Hayashi YK, Yamauchi N, Waki H, Fukayama M, Nishino I, Tokuyama K, Ueki K, Oike Y, Ishii S, Hirose K, Shimizu T, Touhara K, Kadowaki T: Adiponectin and AdipoR1 regulate PGC1a and mitochondria by Ca2+ and AMPK/SIRT1
Nature 464: 1313-1319, 2010
Kubota T, Kubota N, Kumagai H, Yamaguchi S, Kozono H, Takahashi T, Inoue M, Itoh S, Takamoto I, SasakoT, Kumagai K, Kawai T, Hashimoto S, Kobayashi T, Sato M, Tokuyama K, Nishimura S, Tsunoda M, Ide T, Murakami K, Yamazaki T, Ezaki O, Kawamura K, Masuda H, Moroi M, Sugi K, Oike Y, Shimokawa H, Yanagihara N, Tsutsui M, Terauchi Y, Tobe K, Nagai R, Kamata K, Inoue, K Kodama T, Ueki K, Kadowaki T: Impaired insulin signaling in the endothelial cells reduces insulin-induced glucose uptake by the skeletal muscle.
Cell Metabolism 13: 294-307, 2011
 
高坂新一 国立精神・神経医療研究センター・理事
(兼)神経研究所長
神経化学
Namba T, Ming GL, Song H, Waga C, Enomoto A, Kaibuchi K, Kohsaka S, and Uchino S.:
NMDA receptor regulates migration of newly generated neurons in the adult hippocampus via /Disrupted-In-Schizophrenia 1/ (DISC1).
J Neurochem 118 (2011) 34-44.
Sanagi T, Nakamura Y, Suzuki E, Uchino S, Aoki M, Warita H, Itoyama Y, Kohsaka S, Ohsawa K.:
Involvement of activated microglia in increased vulnerability of motoneurons after facial nerve avulsion in presymptomatic amyotrophic lateral sclerosis model rats.
Glia. 60(2012) 782-793.
Ohsawa K, Sanagi T, Nakamura Y, Suzuki E, Inoue K, Kohsaka S.:
Adenosine A3 receptor is involved in ADP-induced microglial process extension and migration.
J Neurochem. 121 (2012) 217-227.
 
品川 邦汎 岩手大学農学部 名誉教授
食品微生物学、獣医公衆衛生学
Submucosal mast cells in the gastrointestinal tract are a target
of staphylococcal enterototoxin type A. FEMS Immunol.Med.Microbiolo., 64,392-402:2012, H.Ono, M.Nishizawa, Y.Yamamoto, D.-L.Hu, A.Nakane, K.Shinagawa, K.Omoe
Superantigenic activity of toxic shock syndrome toxin-1 is resistant to heating and digestive enzymes.   J.Appl.Microbiol.
 110,729-736:2011,  Sj.Li, D.-L.Hu, E.K.Maina, K.Shinagawa, K.Omoe, A.Nakane
新・食肉衛生検査マニュアル. 2011, 全国食肉衛生検査所協議会編
品川邦汎,土肥 暁 編集委員長  中央法規出版 
 
品川 森一 帯広畜産大学名誉教授・(前)動物衛生研究所プリオン病研究センター長
病原微生物学、獣医公衆衛生学
Scrapie, Chronic Wasting Disease, and Transmissible Mink
Encephalopathy. In Prion Biology and Diseases. Laplanche, J.-L.,
Hunter, N., Shinagawa, M., Williams, E. Monograph 38 (Prusiner, S.B.
ed), pp. 393-429, Cold Spring Harbor Laboratory Press, New York
(1999).
プリオン病、品川森一 「食品由来感染症と食品微生物」仲西寿男・丸山努(編)中央法規出版、p.589-611 (2009).
プリオン性人獣共通感染症、品川森一 「改訂版 人獣共通感染症」木村哲・喜田宏(編)医薬ジャーナル社、p.168-173 (2011).
 
豊田 正武 国立医薬品食品衛生研究所 名誉所員
衛生化学
Profiles of potentially antiallergic flavonoids in 27 kinds of health tea and green tea infusions.  Toyoda M. Tanaka K. Hoshino K.  Akiyama H.  Tanimura A.  Saito Y.        J. Agric. Food. Chem. 1997:45:2561‐2564
日本における食事経由のPCDDs、PCDFs及びCoplanar PCBsの摂取量  豊田正武、内部博泰、柳俊彦、河野洋一、堀就英、飯田隆雄 食品衛生学雑誌 1999 : 40(1) : 98-110
食品のアレルギー検査技術−公定法や迅速検査技術の開発状況や動向について 豊田正武、穐山浩 「食品検査とリスク回避のための防御技術」シー・エム・シー出版 p.160−172(2006)
 
永井 良三 自治医科大学・学長
内科学・循環器内科学
Takeda N, Manabe I, Uchino Y, Eguchi K, Matsumoto S, Shindo T, Sano M, Otsu K, Snider P, Conway SJ, Nagai R  Cardiac fibroblasts are essential for the adaptive response of the heart to pressure overload.
J Clin Invest 2010: 120: 254-265
Fujiu K, Manabe I, Nagai R.   Renal collecting duct epithelial cells regulate inflammation in tubulointerstitial damage in mice.. 
J Clin Invest. 2011; 121(9):3425-3441
Eguchi K, Manabe I, Oishi-Tanaka Y, Ohsugi M, Kono N, Ogata F, Yagi N, Ohto U, Kimoto M, Miyake K, Tobe K, Arai H, Kadowaki T, Nagai R. Saturated fatty acid and TLR signaling link β cell dysfunction and islet inflammation.
Cell Metab. 2012; 15(4):518-533
 
長尾 美奈子 慶応義塾大学薬学部・共同研究員
食品中発がん物質の検出
Food Borne Carcinogens Heterocyclic Amines. Edited by Minako Nagao and Takashi Sugimura, John Wiley & Sons, Ltd. Chichester (England)
 Pp1-373. 2000.
Carcinogenic action of N-methyl-N’-nitro-N-nitrosoguanidine, T Sugimura, M Nagao and Y Okada, Nature, 210, 962-963, 1966
「がんと人間」 杉村 隆、垣添 忠生、長尾美奈子 岩波書店
1997年
 
那須 民江 名古屋大学名誉教授・中部大学客員教授
環境毒性学
旧姓Nakajimaを使用しています
Nakajima T, Hopf NB, Schulte PA.
Di(2-ethylhexyl) Phthalate (DEHP). pp183-195. In Identification of research needs to resolve the carcinogenicity of high-priority IARC carcinogens. View and Expert Opinions of an IARC/NORA expert group meeting. 2010)
Yanagiba Y, Ito Y, Yamanoshita O, Zhang SY, Watanabe G, Taya K, Li CM, Inotsume Y. Kamijima M, Gonzalez, FJ, Nakajima T
Styrene trimer may increase thyroid hormone levels via down-regulation of the aryl hydrocarbon receptor (AhR) target gene UDP-glucuronosyltransferase. Environ Health Perspect 2008 Jun;116(6):740-745
Zhang SY, Ito Y, Yamanoshita O, Yanagiba Y, Kobayashi M, Taya K, Li CM, Okamura A, Miyata M, Ueyama J, Lee CH, Kamijima M, Nakajima T
Permethrin May Disrupt Testosterone Biosynthesis via Mitochondrial Membrane Damage of Leydig Cells in Adult Male Mouse.
Endocrinology. 148(8): 3941-3919, 2007
 
早川 堯夫 近畿大学薬学総合研究所・所長
生物化学
Kinoshita M, Ohta H, Higaki K, Kojima Y, Urashima T, Nakajima K, Suzuki M, Kovacs KM, Lydersen C, Hayakawa T, Kakehi K.:Structural characterization of multi-branched oligosaccharides from seal milk by combination of off-line HPLC-MALDI-TOF MS and sequential exoglycosidase digestion. Anal Biochem., 388, 242-53 (2009)
Shibata H, Yoshioka Y, Ohkawa A, Minowa K, Mukai Y, Abe Y, Taniai M, Nomura T, Kayamuro H, Nabeshi H, Sugita T, Imai S, Nagano K, Yoshikawa T, Fujita T, Nakagawa S, Yamamoto A, Ohta T, Hayakawa T, Mayumi T, Vandenabeele P, Aggarwal BB, Nakamura T, Yamagata Y, Tsunoda S, Kamada H, and Tsutsumi Y.: Creation and X-ray structure analysis of the tumor necrosis factor receptor-1-selective mutant of a tumor necrosis factor-alpha antagonist, J Biol Chem., 283,998-1007(2008)
Nakamura T., Peng K-W., Vongpunsawad S., Mizuguchi H., Hayakawa T,, Cattaneo R., and Russell S.J.: Antibody-targeted cell fusion, Nature Biotech., 22, 331-336 (2004)
 
廣田 良夫 大阪市立大学大学院医学研究科・教授
疫学(感染症、骨・関節疾患、難病)
Dietary pattern and risk of Parkinson's disease: a case-control study in Japan. Okubo H, Miyake Y, Sasaki S, Murakami K, Tanaka K, Fukushima W, Kiyohara C, Tsuboi Y, Yamada T, Oeda T, Shimada H, Kawamura N, Sakae N, Fukuyama H, Hirota Y, Nagai M and the Fukuoka Kinki Parkinson's Disease Study Group. Europ J Neurol. 19:681-688, 2012.
Maternal dietary patterns in pregnancy and fetal growth in Japan: the Osaka Maternal and Child Health Study. Okubo H, Miyake Y, Sasaki S, Tanaka K, Murakami K, Hirota Y and Osaka Maternal and Child Health Study Group. Br J Nutr. 107:1526–1533, 2012.
Maternal B vitamin intake during pregnancy and wheeze and eczema in Japanese infants aged 16-24 months: The Osaka Maternal and Child Health Study. Miyake Y, Sasaki S, Tanaka K, Hirota Y. Pediatr Allergy Immunol. 22:69-74, 2011.
福島 昭治 中央労働災害防止協会
日本バイオアッセイ研究センター・所長
化学発がん
Lack of a dose-response relationship for carcinogenicity in the rat liver with low doses of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline or N-nitrosodiethylamine.  Fukushima, S., Wanibuchi, H., Morimura, K., Wei, M., Nakae, D., Konishi, Y., Tsuda, H., Uehara, N., Imaida, K., Shirai, T., Tatematsu, M., Tsukamoto, T., Hirose, M., Furukawa, F., Wakabayashi, K. and Totsuka, Y.: Jpn. J. Cancer Res. 93, 1076-1082, 2002.
Existence of a threshold for induction of aberrant crypt foci in the rat colon with low doses of 2-amino-1-methyl-6-phenolimidazo[4,5-b]pyridine. Fukushima, S., Wanibuchi, H., Morimura, K., Iwai, S., Nakae, D., Kishida, H., Tsuda, H., Uehara, N., Imaida, K., Shirai, T., Tatematsu, M., Tsukamoto, T., Hirose, M. and Furukawa, F.: Toxicol. Sci., 80, 109-114, 2004.
Hormesis and dose-response-mediated mechanisms in carcinogenesis: evidence for a threshold in carcinogenicity of non-genotoxic carcinogens.  Fukushima, S., Kinoshita, A., Puatanachokchai, R., Kushida, M., Wanibuchi, H. and Morimura, K.: Carcinogenesis, 26, 1835-1845, 2005.
 
吉川 泰弘 千葉科学大学・副学長
獣医学、危機管理学
Toyoshima Y, Sekiguchi S, Negishi T, Nakamura S, Ihara T, Ishii Y, Kyuwa S, Yoshikawa Y, Takahashi K. Differentiation of neural cells in fetal cerebral cortex of cynomolgus monkeys (Macaca fascicularis). Comparative Medicine. 62:53-60, 2012
Yoshikawa, Y., Horiuchi, M., Ishiguro, N., Kadohira, M., Kai, S., Mizusawa, H., Nagata, C., Onodera, T., Sata, T., Tsutsui, T., Yamada, M., Yamamoto,S. Alternative risk assessment methodology for beef and beef offal imported into Japan, J. Vet, Med, Sci., 74, 959-968, 2012
Okamura, M., Matsumoto,W., Seike, F., Tanaka,Y., Teratani,C., Tozuka, M., Kashimoto, T., Takehara,K., Nakamura M., Yoshikawa, Y. Efficacy of Soluble Recombinant FliC Protein from Salmonella enterica Serovar Enteritidis as a Potential Vaccine Candidate Against Homologous Challenge in Chickens. Avian Diseases, 56, 354-358, 2012

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