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| 大島 悦男 |
協和発酵キリン（株）執行役員・研究本部長
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| 医薬品化学、有機合成化学、天然物化学 |
Synthesis and Antiallergic Activity of 11-(Aminoalkylidene)-6,11-
dihydrodibenz[b,e]oxepin Derivatives.
Ohshima, E.; Otaki, S.; Sato, H.; Kumazawa, T.; Obase, H.; Ishii, A.; Ishii, H.; Ohmori, K.; Hirayama, N. J. Med. Chem. 1992, 35, 2074–2084. |
Non-prostanoid Thromboxane A2 Receptor Antagonists with a Dibenzoxepin Ring System. 2.
Ohshima, E.; Takami, H.; Sato, H.; Mohri, S.; Obase, H.; Miki, I.; Ishii, A.; Shirakura, S.; Karasawa, A.; Kubo, K. J. Med. Chem. 1992, 35, 3402–3413. |
| Synthesis of 1α-Fluorovitamin D3. Ohshima, E.; Takatsuto, S.; Ikekawa, N.; DeLuca, H. F. Chem. Pharm. Bull. 1984, 32, 3518–3524. |
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| 倉田 毅 |
国際医療福祉大学塩谷病院中央検査部 部長 |
| ウイルス感染症 |
| Intranasal administration ofadjyvant-combined vaccine protects Monkeys from challenge with the highly pathogenic infkuenza A H5N1
Virus. Ichinihe T. Ainai A. Ami Y Nagata N.Iwata N.Kawaguchi A. Suzuki Y. Odagiri T.Tashiro M.Takahashi H. Strayer DR.Carter WA.Chia j.Tamura S. Sata T. Kurata T. Hasegawa H. J.Med.Virol.2010.82:1754-1761. |
| Continuity and change of Japanese encephalitis virus in Toyama pre-Fecture.Japan. Obara M. Yamauchi T. Watanabe M. Hasegawa S. Ueda Y. Matsuno K. Iwai M. Horimoto E. Kurata T. Takizawa T. Kariwa H. Takashima I. American J. Trop. Med. & Hygiene 2011. 84:695-708 |
| Characterization of neutralizing antibodies in adults after intranasal vaccination with an inactivated infkuennza vacnine. Ainai A. Tamura S. Suzuki T. Ito R. Asanuma H.,Tanimoto T.Gomi Manabe S. Ishikawa T.Okuno Y. Odagiri T. Tashiro M.Sata T.Kurata T. And Hasegawa H. J. Med. Virol.2012. 84.336-344 |
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| ○ |
| 高坂 新一 |
国立精神・神経医療研究センター・理事
(兼)神経研究所長
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| 神経化学 |
Namba T, Ming GL, Song H, Waga C, Enomoto A, Kaibuchi K, Kohsaka S, and Uchino S.:
NMDA receptor regulates migration of newly generated neurons in the adult hippocampus via /Disrupted-In-Schizophrenia 1/ (DISC1).
J Neurochem 118 (2011) 34-44. |
Sanagi T, Nakamura Y, Suzuki E, Uchino S, Aoki M, Warita H, Itoyama Y, Kohsaka S, Ohsawa K.:
Involvement of activated microglia in increased vulnerability of motoneurons after facial nerve avulsion in presymptomatic amyotrophic lateral sclerosis model rats.
Glia. 60(2012) 782-793. |
Ohsawa K, Sanagi T, Nakamura Y, Suzuki E, Inoue K, Kohsaka S.:
Adenosine A3 receptor is involved in ADP-induced microglial process extension and migration.
J Neurochem. 121 (2012) 217-227. |
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| 佐竹 元吉 |
お茶の水女子大学 生活環境教育研究センター
客員教授 |
| 薬用植物学 |
| 日本の有毒植物 株）学研教育出版(2012年 5月) |
| André J. Zaharenko, Gisele Picolo, Wilson A. Ferreira, Jr., Takanori Murakami, Kohei Kazuma, Masaru Hashimoto, Yara Cury, José C. De Freitas, Motoyoshi Satake, and Katsuhiro Konno, Bunodosine 391:An Analgesic Acylamino Acid from the Venom of the Sea Anemone Bunodosoma cangicum, J. Nat. Prod, 74, 378-382 (2011) |
| Osamu Shirota, Jennifer M. Oribello, Setsuko Sekita, and Motoyoshi Satake , Sesquiterpenes from Blumea balsamifera, J. Nat. Prod., 74, 470-476 (2011) |
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| 早川 堯夫 |
近畿大学薬学総合研究所所長 |
| 生物化学、薬学 |
| ヒト幹細胞を用いた細胞・組織加工医薬品等の品質・安全性確保に関する指針整備と主なポイント.（その１）−（その８）．早川堯夫、青井貴之、梅澤明弘、小澤敬也、佐藤陽治、澤 芳樹、松山晃文、大和雅之、山中伸弥、再生医療、10(3), 86-152 (2011) |
| Japanese Regulatory Perspective on Immunogenicity. Detection and Quantification of Antibodies to Biopharmaceuticals : Practical and Applied Considerations (ed. by Michael G. Tovey), Takao Hayakawa and Akiko Ishii: John Wiley & Sons, Inc., New Jersey, USA, August 2011 |
| A Possible Role for Protein Phosphorylation in the Activation of the Respiratory Burst in Human Neutrophils: Evidence from studies with cells from patients with chronic granulomatous disease, T. Hayakawa, K. Suzuki, S. Suzuki, P.C. Andrews and B.M. Babior: J. Biol. Chem., 261(20), 9109-9115 (1986) |
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| 福重 潤一郎 |
第一三共株式会社研究開発業務部主査
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| 実験動物 |
| 悪性腫瘍患者の結核症. 福重潤一郎, 丸山孝一, 川上浩 他, 癌の臨床32: 234〜240, 1986. |
| HMG-CoA還元酵素阻害剤の開発から最新知見まで HMG-CoA還元酵素阻害剤の動物による安全性評価．福重潤一郎, 谷吉朗, Prog Med．1998 May；18（5）：1018-1022. |
| ウサギ腎近位尿細管細胞の初代培養と各種抗生剤の細胞毒性. 水野初枝，福重潤一郎，横山富久，吉田由美子, 日本動物実験代替法学会第 8回大会, 1994 |
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| 山口 一成 |
熊本大学発生医学研究所・学術研究員 |
| 血液学、ウイルス学、ワクチン、感染症 |
| Polycomb-mediated loss of miR-31 activates NIK-dependent NF-kB pathway in adult T-cell leukemia and other cancers. Yamagishi M, Nakano K, Miyake A, Yamochi T, Kagami Y, Tsutsumi A, Matsuda Y, Sato-Otsubo A, Muto S, Utsunomiya A, Yamaguchi K, Uchimaru K, Ogawa S, Watanabe T. Cancer Cell 21(1): 121-135,2012 |
| Current prevalence of HTLV-1 in Japan as determinined by screening of blood donors. Satake M, Yamaguchi K, Tadokoro K. J Med Virol 84(2):327-35,2012 |
| HCV infection and B-cell lymphomagenesis. Ito M, Kusunoki H, Mochida K, Yamaguchi K, Mizuochi T: Advances in Hematology 2011 July 20 10.1155 |
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| 山西 弘一 |
医薬基盤研究所・理事長
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| ウイルス学、ワクチン学 |
Intranasal immunization with a formalin-inactivated human influenza a virus whole-virion vaccine alone and intranasal immunization with a split-virion vaccine with mucosal adjuvants show similar levels of cross-protection.
Okamoto S, Matsuoka S, Takenaka N, Haredy AM, Tanimoto T, Gomi Y, Ishikawa T, Akagi T, Akashi M, Okuno Y, Mori Y, Yamanishi K.
Clin Vaccine Immunol. 19、:979-90. 2012 |
Rapid and efficient introduction of a foreign gene into bacterial artificial chromosome-cloned varicella vaccine by Tn7-mediated site-specific transposition.
Somboonthum P, Koshizuka T, Okamoto S, Matsuura M, Gomi Y, Takahashi M, Yamanishi K, Mori Y.
Virology. 402 :215-21、2010 |
A community-based survey of varicella-zoster virus-specific immune responses in the elderly.
Tang H, Moriishi E, Okamoto S, Okuno Y, Iso H, Asada H, Yamanishi K, Mori Y; for the Shozu Herpes Zoster (SHEZ) Study group.
J Clin Virol. In press 2012 |
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| 吉木 淳 |
理化学研究所バイオリソースセンター・実験動物開発室長
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| 実験動物学、動物遺伝学 |
| Cao, L., Kobayakawa, S., Yoshiki, A. &Abe, K. (2012). High resolution intravital imaging of subcellular structures of mouse abdominal organs using a microstage device. PLoS One 7(3): e33876. |
| Kasahara, T., Abe, K., Mekada, K., Yoshiki, A. &Kato, T. (2010). Genetic variation of melatonin productivity in laboratory mice under domestication. Proc Natl Acad Sci U S A 107(14): 6412-6417. |
| Yoshiki, A., Ike, F., Mekada, K., Kitaura, Y., Nakata, H., Hiraiwa, N., Mochida, K., Ijuin, M., Kadota, M., Murakami, A., Ogura, A., Abe, K., Moriwaki, K. &Obata, Y. (2009). The mouse resources at the RIKEN BioResource center. Exp Anim 58(2): 85-96. |
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