ホーム > 政策について > 分野別の政策一覧 > 他分野の取り組み > 研究事業 > 以前(平成9〜22年度)厚生労働科学研究費補助金の概要 > 平成22年度厚生労働科学研究費補助金の概要 > 事前評価委員会名簿 > 難治性疾患克服研究事業事前評価委員名簿

難治性疾患克服研究事業事前評価委員名簿

(○:委員長)

 
池田 康夫 早稲田大学理工学術院 先進理工学研究科 生命理工学研究専攻 教授
血栓止血学
Ikeda, Y., Handa, M., Kawano, K., Kamata, T., Murata, M., Araki, Y., Ambo, H., Kawai, Y., Watanabe, K., Itagaki, I., Sakai, K., and Ruggeri, Z.M.:
The role of von Willebrand factor and fibrinogen in platelet aggregation under varying shear stress.
J. Clin. Invest. 87:  1234-1240, 1991
Bhatt DL., Steg PG., Ohman EM., Hirsch AT., Ikeda, Y., Mas JL., Goto S., Liau CS., Richard AJ., Rother J., Wilson PWF., for the REACH Registry Investigators. :
International prevalence, recognition, and treatment of cardiovascular risk factors in outpatients with atherothrombosis. 
JAMA 295 (2): 180-189, 2006 (1).
Ikeda Y and Miyakawa Y:  Development of thrombopoietin receptor agonists for clinical use.  J Thromb Haemost 7 (sup.1) 239-244, 2009
 
稲葉 裕 実践女子大学生活科学部 教授
疫学
「疫学調査における地域および年令因子に関する研究」稲葉 裕、高木廣文、柳井晴夫、松原純子.日本公衛誌 22(2),83-90. 1975
Recent statistical data book of intractable diseases in Japan.
Inaba Y, Minowa M, Osaki Y, Nagai M, Aizawa S, Ohno Y(Eds)
Research Committee on Epidemiology of Intractable Diseases, the Ministry of Health and Welfare of Japan.1996
「難病とその他の疾患」稲葉裕編著.所収「疫学ハンドブック:重要疾患の疫学と予防」日本疫学会編.1998
 
内田 健夫 (社)日本医師会 常任理事
外科
【どうなる 特定健診・特定保健指導】【特定健診・特定保健指導への対応】日本医師会の立場から.内田健夫.病院.67(7).609-611.2008
【特定健診・特定保健指導の実際】保健指導の実際 地域における特定保健指導.内田健夫.綜合臨床.57(5).1612-1617.2008
ヘルスサービスの中のジェネリック医薬品 医療政策から臨床の場まで ジェネリック医薬品の問題点について.内田健夫.薬理と治療.35 (3).1047-1050.2007
 
春日 雅人 国立国際医療研究センター 研究所長
内科学、内分泌代謝学
Dok1 mediates high-fat diet–induced adipocyte hypertrophy and obesity through modulation of PPAR-γ phosphorylation.  Hosooka, T., Noguchi, T., Kotani, K., Nakamura, T., Sakaue, H., Inoue, H., Ogawa, W., Tobimatsu, K., Takazawa, K., Sakai, M., Matsuki, Y., Hiramatsu, R., Yasuda, T., Lazar, MA., Yamanashi, Y.and Kasuga, M.  Nature Med. (2008)14:188-193.
FSP27 Contributes to efficient energy storage in murine white adipocytes by promoting the formation of unilocular lipid droplets. Nishino, N., Tamori, Y., Tateya, S., Kawaguchi, T., Shibakusa, T., Mizunoya, W., Inoue, K., Kitazawa, R., Kitazawa, S., Matsuki, Y., Hiramatsu, R., Masubuchi, S., Omachi, A., Kimura, K.,  Saito, M., Amo, T., Ohta, S., Yamaguchi, T., Osumi, T., Cheng, J., Fujimoto, T., Nakao, H., Nakao, K., Aiba, A., Okamura, H., Fushiki, T., and Kasuga, M.  J.Clin.Invest.(2008)118:2808-2821.
Ablation of C/EBPb alleviates ER stress and pancreatic b cell failure through induction of GRP78.  Matsuda T, Kido Y, Asahara S, Kaisho T, Tanaka T, Hashimoto N, Shigeyama Y, Takeda A, Inoue T, Shibutani Y, Koyanagi M, Hosooka T, Matsumoto M, Inoue H, Uchida T, Koike M, Uchiyama Y, Akira S, Kasuga M.  J. Clin. Invest. (2010)120: 115-126
 
木下 茂 京都府立医科大学・視覚機能再生外科学教授
眼科学
Kinoshita S, Adachi W, Sotozono C, Nishida K, Yokoi N, Quantock A, Okubo K: Characteristics of the human ocular surface epithelium. Prog. Retina Eye Res 20:639-673, 2001.
Sotozono C, Ueta M, Koizumi N, Inatomi T, Ikezawa Z, Shirakata Y, Hashimoto K, Kinoshita S: Diagnosis and Treatment of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis with Ocular Complications. Ophthalmology  116:685-690, 2009.
Nakano M, Ikeda Y, Taniguchi T, Yagi T, Fuwa M, Omi N, Tokuda Y, Tanaka M, Yoshii K, Kageyama M, Naruse S, Matsuda A, Mori K, Kinoshita S, Tashiro K: Three susceptible foci associated with primary-open angle glaucoma identified by genome-wide association study in Japanese population. Proc Natl Acad Sci 106:12838-12842, 2009.
葛原 茂樹 鈴鹿医療科学大学 保健衛生学部医療福祉学科 特任教授
神経変性疾患、痴呆性疾患、医原性神経疾患、脳血管障害
Kuzuhara S, Kokubo Y, Sasaki R, Narita Y, Yabana T, Hasegawa M, Iwatsubo
T: Familial amyotrophic lateral sclerosis and parkinsonism-dementia complex
of the Kii peninsula of Japan: clinical and neuropathological study and tau
analysis. Ann Neurol 49:501-511, 2001
Morimoto S, Kuzuhara S, Kokubo Y: Increased oxidative stress in patients
with amyotrophic lateral sclerosis/parkinsonism-dementia comlex in the
Kii Peninsula, Japan. Mov Disord 24:123-126, 2008
Tomiyama H, Kokubo Y, Sasaki R, Li Y, Imamichi Y, Funayama M, Mizuno Y,
Hattori N, Kuzuhara S: Mutation analyses in amyotrophic lateral
sclerosis/parkinsonism-dementia complex of the Kii peninsula, Japan. Mov
Disord 23:2344-2348, 2008
 
齊藤 延人 東京大学教授
脳神経外科
Kin T, Oyama H, Kamada K, Aoki S, Ohtomo K, Saito N. Prediction of surgical view of neurovascular decompression using interactive computer graphics. Neurosurgery 65:121-128, 2009.
Tanaka Y, Imai H, Konno K, Miyagishima T, Kubota C, Puentes S, Aoki T, Hata H, Takata K, Yoshimoto Y, Saito N. Experimental Model of Lacunar Infarction in the Gyrencephalic Brain of the Miniature Pig: Neurological Assessment and Histological, Immunohistochemical, and Physiological Evaluation of Dynamic Corticospinal Tract Deformation. Stroke 39: 205-212, 2008.
Saito N, Okada Y, Noda Y, Kinoshita Y, Kondo S, Hirokawa N.  KIFC2 is a novel neuron-specific C-terminal type kinesin superfamily motor for dendritic transport of multivesicular body-like organelles. Neuron 18: 425-438, 1997.
 
清野 裕 関西電力病院 院長
糖尿病学
Inhibition of gastric inhibitory polypeptide signaling prevents obesity
Miyawaki K, Yamada Y, Ban N, Ihara Y, Tsukiyama K, Zhou H, Fujimoto S, Oku A, Tsuda K, Toyokuni S, Hiai H, Mizunoya W, Fushiki T, Holst JJ, Makino M, Tashita A, Kobara Y, Tsubamoto Y, Jinnouchi T, Jomori T, Seino Y.
Nat Med. 2002 Jul;8(7):738-42. Epub 2002 Jun 17.
Glucose intolerance caused by a defect in the entero-insular axis: a study in gastric inhibitory polypeptide receptor knockout mice
Miyawaki K, Yamada Y, Yano H, Niwa H, Ban N, Ihara Y, Kubota A, Fujimoto S, Kajikawa M, Kuroe A, Tsuda K, Hashimoto H, Yamashita T, Jomori T, Tashiro F, Miyazaki J, Seino Y.  Proc Natl Acad Sci U S A. 1999 Dec 21;96(26):14843-7.
Overexpression of inducible cyclic AMP early repressor inhibits transactivation of genes and cell proliferation in pancreatic beta cells
Inada A, Hamamoto Y, Tsuura Y, Miyazaki J, Toyokuni S, Ihara Y, Nagai K, Yamada Y, Bonner-Weir S, Seino Y 
Mol Cell Biol. 2004 Apr;24(7):2831-41
 
清野 佳紀 大阪厚生年金病院 名誉院長
小児科学、内分泌学
Evaluation of Quality of Life in Children with GH Deficiency and Idiopathic Short Stature Using the Child Behavior Checklist.
Toshiaki Tanaka, ShigeruTai, Yoji Morisaki, Katsuhiko Tachibana,Yasuko Kambayashi, Kazuo Chigara, YoshikiSeino, and Kenji Fujieda. Clin Pediatr Endocrinol 18(1), 15-22. 2009.
PTH has the potential to rescue disturbed bone growth in a achondroplasia. Koso Ueda, Yoshitaka Yamanaka, Daisuke Harada, Emi Yamagami, Hiroyuki Tanaka, Yoshiki Seino. Bone 41.13-18.2007.
「NEW 小児科学 改訂2版」清野佳紀、小林邦彦、原田研介、桃井眞理子.南江堂.2009.
 
竹中 洋 大阪医科大学 学長
耳鼻咽喉科学
Enhanced human IgE production results from exposure to the aromaticHydrocarbons from diesel exhaust;direct effects on B-cell IgE production, Takenaka H,et al
J Allery CLin Immunol;1998.95:103-115.
コア・ローテイション 耳鼻咽喉科・頭頸部外科
編集 竹中洋、高橋姿、久育男
金芳堂、2004年1月5日
気道アレルギーの成立とその制御:竹中 洋
第110回日本耳鼻咽喉科学術総会宿題報告
東京、2009.05.14.
 
友池 仁暢 国立循環器病研究センター 名誉院長
循環器内科学
Kawai T, Ito T, Ohwada K, Mera Y, Matsushita M, Tomoike H. Hereditary postprandial hypertriglyceridemic rabbit exhibits insulin resistance and central obesity. A novel model of metabolic syndrome. Arterioscler Thromb Vasc Biol 2006;26:2752-2757.
Kitakaze M, Asakura M, Kim J, Shintani Y, Asanuma H, Hamasaki T, Tomoike H, et al. Human atrial natriuretic peptide and nicorandil as adjuncts to reperfusion treatment for acute myocardial infarction (J-WIND): two randomised trials. Lancet 2007;370:1483-1493.
Harada-Shiba M, Sugisawa T, Makino H, Abe M, Tsushima M, Yoshimasa T, Yamashita T, Miyamoto Y, Yamamoto A, Tomoike H, Yokoyama S. Impact of statin treatment on the clinical fate of heterozygous familial hypercholesterolemia. J Atheroscler Thromb 2010;17:667-674.
 
西岡 清 横浜市立みなと赤十字病院 名誉院長
皮膚科学・免疫アレルギー学
Hepatocyte growth factor both prevents and ameliorates the symptoms of dermal sclerosis in a mouse model of scleroderma.  Wu MH, Yokozeki H, Takagawa S, Yamamoto T, Satoh T, Kaneda Y, Katayama I, Nishioka K  Gene Therapy 11: 170-180, 2004
Synthesis of α(1,3) fucosyltransferases IV- and VII-dependent eosinophil selectin ligand and recruitment to the skin.  Satoh T, Kanai Y, Wu M-H, Yokozeki H, Kannagi R, Lowe JB, Nishioka K   Am J Pathol 167: 787-796, 2005
Prostaglandin D2 plays an essential role in chronic allergic inflammation of the skin via CRTH2 receptor.  Satoh T, Moroi R, Akitake K, Urade Y, Kanai Y, Sumi K, Yokozeki H, Nagata K, Hara T, Utsuyama M, Hirokawa K, Suganuma K, Nishioka K, Nakamura M  J Immunology 177: 2621-2629, 2006
 
貫和 敏博 東北大学大学院医学系研究科・教授
内科学(呼吸器内科学)
Gefitinib or chemotherapy for non-small-cell lung cancer with mutated EGFR. Maemondo M, Inoue A, Kobayashi K, Sugawara S, Oizumi S, Isobe H, Gemma A, Harada M, Yoshizawa H, Kinoshita I, Fujita Y, Okinaga S, Hirano H, Yoshimori K, Harada T, Ogura T, Ando M, Miyazawa H, Tanaka T, Saijo Y, Hagiwara K, Morita S, Nukiwa T; North-East Japan Study Group. N Engl J Med. 2010 Jun 24;362(25):2380-8.
First-line gefitinib for patients with advanced non-small-cell lung cancer harboring epidermal growth factor receptor mutations without indication for chemotherapy. Inoue A, Kobayashi K, Usui K, Maemondo M, Okinaga S, Mikami I, Ando M, Yamazaki K, Saijo Y, Gemma A, Miyazawa H, Tanaka T, Ikebuchi K, Nukiwa T, Morita S, Hagiwara K; North East Japan Gefitinib Study Group. J Clin Oncol. 2009 Mar 20;27(9):1394-400.
OX40 ligand expressed by DCs costimulates NKT and CD4+ Th cell antitumor immunity in mice. Zaini J, Andarini S, Tahara M, Saijo Y, Ishii N, Kawakami K, Taniguchi M, Sugamura K, Nukiwa T, Kikuchi T. J Clin Invest. 2007 Nov;117(11): 3330-8
 
棟方 昭博 弘前大学名誉教授
消化器内科,消化器内視鏡,消化器免疫
Dose portalhypertention modify colonic mucosal vasculature? quantification of alteration by image processing and topology. Munakata A. Sasaki Y. Am. J. Gastroenterology 90:1997-2001, 1995
Improved localizing method of radiopill in measurement of entire gastorointestinal pH profiles: Colonic luminal pH in normal subjects and patient with Crohm’s disease. Sasaki Y, Nakajima H, Munakata A. Am. J. Gastroenterology 92:114-118, 1997
Endoscopic ligation by means of clip and detachable snare for management of colonic postpolypectomy hemorrhage. Uno Y, Munakata A. Gstrointestinal Endoscopy 49:113-115, 1999

ホーム > 政策について > 分野別の政策一覧 > 他分野の取り組み > 研究事業 > 以前(平成9〜22年度)厚生労働科学研究費補助金の概要 > 平成22年度厚生労働科学研究費補助金の概要 > 事前評価委員会名簿 > 難治性疾患克服研究事業事前評価委員名簿

ページの先頭へ戻る