第3次対がん総合戦略研究事業 事前評価委員名簿
(○:委員長)
上田龍三 | 名古屋市立大学大学院医学研究科・教授 |
腫瘍内科、分子標的治療、抗体療法 | |
Yano, H., Ishida, T., Inagaki, A., Ishii, T., Ding, J., Kusumoto, S., Komatsu, H., Iida, S., Inagaki, H., Ueda, R.: Defucosylated Anti CC Chemokine Receptor 4 Monoclonal Antibody Combined with Immunomodulatory Cytokines: A Novel Immunotherapy for Aggressive/Refractory Mycosis Fungoides and Sezary Syndrome. Clin Cancer Res. 13(21): 6494-6500, 2007 | |
Oguri T., Ozasa H., Uenura T., Miyazaki M., Maeso K., Maeda H., Ueda R.: MRP7/ABCC10 expression is predictive biomarker for the resistance to padlotaxel in non-small cell lung cancer. Mol Cancer Ther. 7(5): 1150-5, 2008 | |
Zhao, C., Inoue, J., Imoto, I., Otsuki, T., Iida, S., Ueda, R. and Inazawa, J. : POU2AF1, an amplification target at 11q23, priomotes growth of multiple myeloma cells by directly regulating expression of a B-cell maturation factor, TNFRSF17. Oncogene. 27(1): 63-75, 2008 |
児玉 哲郎 | 栃木県立がんセンター所長 |
臨床腫瘍学 | |
Endobronchial polypoid adenocarcinoma of the lung. Histological and ultrastructural studies of five cases. Kodama T, Shimosato Y, Koide T, Watanabe S, and Yoneyama T Am J Surg Pathol 1984 8:845-854. | |
肺腺癌と異型増殖性病変、その病理組織学的検討 児玉哲郎、西山祥行、西脇 裕、高橋健郎、黒木基夫、村杉雅秀、林辺 晃、忽滑谷直孝、北谷知己、松山智治 肺癌 1988 28:325-333. | |
Pro-gastrin-releasing peptide (31-98) is a specific tumor marker in patients with small cell lung carcinoma. Miyake Y, Kodama T, Yamaguchi K: Cancer Res, 1994 54:2136-2140. |
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澁谷正史 | 上武大学副学長、東京医科歯科大学客員教授 |
分子生物学、血管生物学 | |
MMP9 induction by Vascular Endothelial Growth Factor Receptor-1 is involved in lung specific metastasis. Hiratsuka, S., Nakamura, K., Iwai, S., Murakami, M., Itoh, T., Kijima, H., Shipley, J. M., Senior, R. M., and Shibuya, M. Cancer Cell, 2 (Oct.), 289-300, 2002. | |
A single autophosphorylation site on KDR/Flk-1 is essential for VEGF-A-dependent activation of PLC-? and DNA synthesis in vascular endothelial cells. Takahashi, T., Yamaguchi, S., Chida, K., and Shibuya, M. EMBO J., 20 (11), 2768-2778, 2001. | |
Amplification of the structurally and functionally altered epidermal growth factor receptor gene (c-erbB) in human brain tumors. Yamazaki, H., Fukui, Y., Ueyama, Y., Tamaoki, N., Kawamoto, T., Taniguchi, S., and Shibuya, M. Mol. Cell. Biol. 8 (4), 1816-1820, 1988. |
下遠野 邦忠 | 慶應義塾大学 医学部 特別研究教授 |
専門分野 分子生物学、分子ウイルス学 | |
Miyanari Y, Atsuzawa K, Usuda N, Watashi K, Hishiki T, Zayas M, Bartenschlager R, Wakita T, Hijikata M, Shimotohno K. The lipid droplet is an important organelle for hepatitis C virus production. Nat Cell Biol. 9(9):1089-1097, 2007 | |
Watashi K, Ishii N, Hijikata M, Inoue D, Murata T, Miyanari Y, Shimotohno K. Cyclophilin B is a functional regulator of hepatitis C virus RNA polymerase. Mol Cell. 19 :111-122, 2005. | |
「C型肝炎ウイルスの増殖戦略」蛋白質核酸酵素 53巻 666-672 (2008) |
高嶋 成光 | (独)国立病院機構 四国がんセンター 院長 |
専門分野 乳腺外科 | |
A phase II study of high-dose Epirubicin plus Cyclophosphamide with G-CSF for breast cancer patients with visceral metastases or hormone-independent tumors: A trial of the Japan Clinical Oncology Group. Takashima S, Saeki T, et al. Jpn Clin Oncol 27:325-330, 1997. | |
Randomized clinical trial comparing level II and level III axially node dissection in addition to mastectomy for breast cancer. Tominaga T, Takashima S, et al. Brit J Surg 91:38-43, 2004. | |
Zoledronic acid significantly reduces skeletal complications compared with placebo in Japanese women with bone metastases from breast cancer: A randomized, placebo-controlled trial. Kohno N, Aogi K, Takashima S, et al. J Clin Oncol 23:3314-3321,2005. |
委員:田島和雄 | 所属・役職:愛知県がんセンター研究所・所長 |
専門分野:がんの疫学・予防 | |
Decreased risk of colorectal cancer with the high Natural-Killer (NK)-cell activity NKG2D genotype in Japanese. Furue H, Matsuo K, Kumimoto H, Hiraki A, Suzuki T, Yatabe Y, Komori K, Kanemitsu Y, Hirai T, Kato T, Ueda M, Ishizaki K, Tajima K.: Carcinogenesis 29: 316-20, 2008. (他400編) | |
がん・統計白書−罹患/死亡/予後−:篠原出版新社、2004年 がん予防の最前線、上巻、下巻:昭和堂、2004年、2005年 がん研究のいま[4]「がんの疫学」:東京大学出版会、2006年 |
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"UICC global initiatives in support of the global action plan against cancer" Tajima K. Symposium "WHO-UICC collaboration in Response to the Cancer Epidemic", UICC World Cancer Congress 2008 "Towards True Cancer Control", Geneva, Switzerland, 27-31, 2008. |
土屋 了介 | 国立がんセンター中央病院・病院長 |
胸部外科学 特に進行肺がんの手術・集学的治療・周術期管理、胸部診断学 | |
Prognosis of Resected Non-Small Cell Lung Cancer Patients with Intrapulmonary Metastases. Nagai K, Sohara Y, Tsuchiya R, Goya T, Miyaoka E. Journal of Thoracic Oncology.2007 2-4 April:282-286 | |
Immunohistochemical detection of GLUT-1 can discriminate between reactive masothelium and malignant mesothelioma. Kato Y, Tsuta K, Seki K, Miyagi A, Maeshima M A, Watanabe S,Suzuki K, Asamura H, Tsuchiya R, Matsuno Y. Modern Pathology. 2007 20:215-220 |
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Low-dose CT screening for lung cancer with automatic exposure control:phantom study. Gomi S, Muramatsu Y, Tsukagoshi S,Suzuki M, Kakinuma R, Tsuchiyua R, Moriyama N. Radiol Phys Technol. 2008 1:244-250 |